Biological properties and surgical applications of the human amniotic membrane

JR Munoz-Torres, SB Martínez-González… - … in Bioengineering and …, 2023 - frontiersin.org
The amniotic membrane (AM) is the inner part of the placenta. It has been used
therapeutically for the last century. The biological proprieties of AM include …

Amniotic membrane and its derivatives: novel therapeutic modalities in liver disorders

MK Arki, K Moeinabadi-Bidgoli, N Hossein-Khannazer… - Cells, 2023 - mdpi.com
The liver is a vital organ responsible for metabolic and digestive functions, protein synthesis,
detoxification, and numerous other necessary functions. Various acute, chronic, and …

[HTML][HTML] The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix

A Shah, X Zhang, M Snee, MP Lockhart-Cairns… - Matrix Biology, 2025 - Elsevier
ABSTRACT Pentraxin-3 (PTX3) is an octameric protein, comprised of eight identical
protomers, that has diverse functions in reproductive biology, innate immunity and cancer …

[HTML][HTML] Cell identity changes in ocular surface Epithelia

N Di Girolamo, M Park - Progress in Retinal and Eye Research, 2023 - Elsevier
Corneal and conjunctival epithelia arise from a common ancestral ectoderm cell, then
diverge into distinct lineages. The former develops into a multilayered stratified squamous …

Targeted analysis of the size distribution of heavy chain-modified hyaluronan with solid-state nanopores

DA Erxleben, RJ Dodd, AJ Day, DE Green… - Analytical …, 2024 - ACS Publications
The glycosaminoglycan hyaluronan (HA) plays important roles in diverse physiological
functions where the distribution of its molecular weight (MW) can influence its behavior and …

PTX3 promotes osteogenic differentiation by triggering HA/CD44/FAK/AKT positive feedback loop in an inflammatory environment

W Dong, X Xu, Y Luo, C Yang, Y He, X Dong, J Wang - Bone, 2022 - Elsevier
The treatment of periodontitis-induced alveolar bone defects remains a clinical challenge.
The secreted protein pentraxin 3 (PTX3) protects tissue during inflammation and maintains …

Hyaluronan‐protein interactions: Lilliput revisited

AJ Day - Proteoglycan Research, 2024 - Wiley Online Library
Hyaluronan (HA) is a huge linear polysaccharide composed entirely of a simple repeating
disaccharide that has been preserved unchanged since the evolution of vertebrates~ 520 …

Various administration forms of decellularized amniotic membrane extract towards improving corneal repair

Y Luo, M Shen, P Feng, H Qiu, X Wu, L Yang… - Journal of Materials …, 2021 - pubs.rsc.org
Amniotic membrane (AM) transplantation is often used as a treatment for corneal repair, but
AM is prone to dissolving and shedding after surgery; multiple transplants will cause pain …

Niche regulation of limbal epithelial stem cells: HC-HA/PTX3 as surrogate matrix niche

SCG Tseng, SY Chen, OG Mead, S Tighe - Experimental eye research, 2020 - Elsevier
Homeostasis of the corneal epithelium is ultimately maintained by stem cells that reside in a
specialized microenvironment within the corneal limbus termed palisades of Vogt. This …

Early three-month report of amniotic bladder therapy in patients with interstitial cystitis/bladder pain syndrome

R Madan, C Radoiu, A Liaw, S Lucas… - … Urology and Nephrology, 2023 - Springer
Background Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by
symptomatic frequency and urgency, as well as chronic pelvic pain. Disruption of the …