Cholinesterase inhibitors as Alzheimer's therapeutics

K Sharma - Molecular medicine reports, 2019 - spandidos-publications.com
Alzheimer's disease (AD) is one of the most common forms of dementia. AD is a chronic
syndrome of the central nervous system that causes a decline in cognitive function and …

[PDF][PDF] Alzheimer's and current therapeutics: A review

A Panche, S Chandra, AD Diwan… - Asian J Pharm Clin Res, 2015 - researchgate.net
In recent past several efforts have been made to analyze the symptoms, causes, and cure of
Alzheimer's disease (AD) and also to reveal biochemical changes and pathogenesis of the …

Multidisciplinary approaches for targeting the secretase protein family as a therapeutic route for Alzheimer's disease

N Schaduangrat, V Prachayasittikul… - Medicinal Research …, 2019 - Wiley Online Library
The continual increase of the aging population worldwide renders Alzheimer's disease (AD)
a global prime concern. Several attempts have been focused on understanding the intricate …

[HTML][HTML] Comprehensive investigation of multiple targets in the development of newer drugs for the Alzheimer's disease

P Ashwini, B Subhash, M Amol, D Kumar… - … Pharmaceutica Sinica B, 2024 - Elsevier
Alzheimer's disease, a significant contributor to dementia, is rapidly becoming a serious
healthcare concern in the 21 st century. The alarming number of patients with Alzheimer's …

Computational approaches for therapeutic application of natural products in Alzheimer's disease

M Awasthi, S Singh, S Tiwari, VP Pandey… - … Modeling of Drugs …, 2018 - Springer
Alzheimer's disease (AD) is characterized by deterioration of cognitive functions and
behavioral changes eventually leading to cell death and dementia. Till date, several efforts …

[PDF][PDF] Molecular Docking Studies of Some Flavonoids of Ginkgo biloba with Proteins Probably Responsible for Alzheimer Disease

S Sharma - academia.edu
Alzheimer disease is one of the most common forms of dementia. βamyloid and tau protein
damage in brain is considered to be responsible for this disease. Some flavonoids like …

[PDF][PDF] International Journal of Trend in Scientific Research and Development (IJTSRD)

A Tripathi, H Nigam, N Khare - academia.edu
In present scenario there are different terminologies which are used for categorizing the
branches of computer aided drug designing like molecular modeling, theoretical chemistry …

[PDF][PDF] FUTURE PERSPECTIVES ON ALZHEIMER'S DISEASE COMPUTATIONAL MODELING–A REVIEW

IM BALMUS, A CIOBÎCĂ, P ALEXIOU… - ACADEMY OF …, 2017 - aos.ro
Abstract Alzheimer's disease (AD), which is one of the most common age–associated
neurodegenerative disorders, has been proven to be of a multifactorial and polygenic …

[PDF][PDF] In-Silico Identification of Potential Inhibitors Against AChE Using Cheminformatics Approach. MOJ Proteomics Bioinform 1 (4): 00022

A Pathak, IH Madar, K Raithatha, JK Gupta - 2014 - researchgate.net
Materials and Methods Preparation of 3D structures 3D structure of AChE was retrieved from
Protein Data Bank PDB_ID: 1B41 (Figure 1). SMILES strings of all 15 drug molecules were …

[引用][C] In-silico identification of potential inhibitors against ache using cheminformatics approach

A Pathak, IH Madar, K Raithatha, JK Gupta - MOJ Proteomics Bioinform, 2014