[HTML][HTML] Repetitive RNAs as regulators of chromatin-associated subcompartment formation by phase separation

L Frank, K Rippe - Journal of molecular biology, 2020 - Elsevier
Repetitive RNA (repRNA) sequences emerge as important regulators of the dynamic
organization of genomic loci into membrane-less subcompartments with distinct nuclear …

A circular RNA-gawky-chromatin regulatory axis modulates stress-induced transcription

R Su, M Zhou, J Lin, G Shan… - Nucleic Acids Research, 2024 - academic.oup.com
In response to heavy metal stress, the RNA-binding protein (RBP) gawky translocates into
the nucleus and acts as a chromatin-interacting factor to activate the transcription of many …

DNA mimic foldamers affect chromatin composition and disturb cell cycle progression

V Kleene, V Corvaglia, E Chacin, I Forne… - Nucleic Acids …, 2023 - academic.oup.com
The use of synthetic chemicals to selectively interfere with chromatin and the chromatin-
bound proteome represents a great opportunity for pharmacological intervention. Recently …

Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin

PB Becker - Biochemical Society Transactions, 2024 - portlandpress.com
Extracts from Drosophila preblastoderm embryos (DREX) form the basis of a powerful in
vitro chromatin reconstitution system that assembles entire genomes into complex chromatin …

The histone fold protein CHRAC-14 controls CENP-A loading and gene expression in Drosophila melanogaster

S Doppler - 2022 - archiv.ub.uni-heidelberg.de
Centromeres are specialized chromatin domains present on each chromosome, which
determine the location of kinetochore formation–the multiprotein platform for spindle …

Characterizing Synthesis-Dependent Microhomology-Mediated End-Joining Requirements Through Signatures of Inaccurate Double Strand Break Repair

TT Hanscom - 2021 - search.proquest.com
DNA is the nucleic acid blueprint in every cell that is essential to all life, and because it is
broken almost constantly through exposure to mutagens like UV, X-rays, and chemicals in …

[PDF][PDF] In vivo functional dissection of CHRAC/ACF and DOMINO chromatin regulators

A Scacchetti - 2020 - edoc.ub.uni-muenchen.de
In vivo functional dissection of CHRAC/ACF and DOMINO chromatin regulators Page 1 Aus dem
Adolf-Butenandt-Institut Lehrstuhl Molekularbiologie im Biomedizinischen Centrum Institut der …