Variation in the mitochondrial DNA (mtDNA) sequence is common in certain tumours. Two
classes of cancer mtDNA variants can be identified: de novo mutations that act as 'inducers' …

Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by a
slow, progressive, and multifactorial degeneration of retinal ganglion cells (RGCs) and their …

Southern Africa is consistently placed as a potential region for the evolution of Homo
sapiens. We present genome sequences, up to 13x coverage, from seven ancient …

Africa is the source of all modern humans, but characterization of genetic variation and of
relationships among populations across the continent has been enigmatic. We studied 121 …

" Offering a wide variety of philosophical approaches to the neglected philosophical problem
of ignorance, this collection builds on Charles Mills's claim that racism involves an inverted …

Human mtDNA shows striking regional variation, traditionally attributed to genetic drift.
However, it is not easy to account for the fact that only two mtDNA lineages (M and N) left …

Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …

The history of click-speaking Khoe-San, and African populations in general, remains poorly
understood. We genotyped∼ 2.3 million single-nucleotide polymorphisms in 220 southern …

The MITOMAP () data system for the human mitochondrial genome has been greatly
enhanced by the addition of a navigable mutational mitochondrial DNA (mtDNA) …

The quest to explain demographic history during the early part of human evolution has been
limited because of the scarce paleoanthropological record from the Middle Stone Age. To …