Polymyalgia rheumatica

G Espígol-Frigolé, C Dejaco, SL Mackie, C Salvarani… - The Lancet, 2023 - thelancet.com
Polymyalgia rheumatica is an inflammatory disease producing pain and stiffness, mainly in
the shoulders and pelvic girdle, in people older than 50 years. Elevation of acute phase …

Clinical features of polymyalgia rheumatica and giant cell arteritis

C Salvarani, N Pipitone, A Versari… - Nature Reviews …, 2012 - nature.com
Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are inflammatory diseases that
typically affect white individuals> 50 years. Women are affected∼ 2–3 times more often than …

Effect of tocilizumab on disease activity in patients with active polymyalgia rheumatica receiving glucocorticoid therapy: a randomized clinical trial

V Devauchelle-Pensec, G Carvajal-Alegria, E Dernis… - Jama, 2022 - jamanetwork.com
Importance Few treatments are available for patients with glucocorticoid-dependent
polymyalgia rheumatica. IL-6 antagonists may reduce disease activity in patients with active …

Efficacy and Safety of Tofacitinib in Patients with Polymyalgia Rheumatica (EAST PMR): An open-label randomized controlled trial

X Ma, F Yang, J Wu, B Xu, M Jiang, Y Sun, C Sun… - PLoS …, 2023 - journals.plos.org
Background Polymyalgia rheumatica (PMR) is a common inflammatory disease in elderly
persons whose mechanism of pathogenesis has not been elucidated. Glucocorticoids are …

Monitoring and long-term management of giant cell arteritis and polymyalgia rheumatica

D Camellino, EL Matteson, F Buttgereit… - Nature Reviews …, 2020 - nature.com
Giant cell arteritis (GCA) is the most common type of primary vasculitis in Western countries.
Polymyalgia rheumatica (PMR) is the second most common inflammatory rheumatic disease …

Efficacy of first-line tocilizumab therapy in early polymyalgia rheumatica: a prospective longitudinal study

V Devauchelle-Pensec, JM Berthelot… - Annals of the …, 2016 - ard.bmj.com
Background Glucocorticoids are the cornerstone treatment of polymyalgia rheumatica (PMR)
but induce adverse events. Objectives To evaluate the efficacy and safety of first-line …

Inflammatory rheumatic diseases with onset after SARS-CoV-2 infection or COVID-19 vaccination: a report of 267 cases from the COVID-19 and ASD group

F Ursini, P Ruscitti, O Addimanda, R Foti… - RMD open, 2023 - rmdopen.bmj.com
Objectives To better define the spectrum of new-onset post-COVID-19 and post-COVID-19
vaccine inflammatory rheumatic diseases (IRD) from a large multicentric observational …

Brief report: a prospective open‐label phase IIa trial of tocilizumab in the treatment of polymyalgia rheumatica

L Lally, L Forbess, C Hatzis… - Arthritis & Rheumatology, 2016 - Wiley Online Library
Objective Interleukin‐6 (IL‐6) is a pivotal cytokine in the pathogenesis of polymyalgia
rheumatica (PMR), yet the efficacy of IL‐6 blockade with tocilizumab (TCZ) for the treatment …

Pathogenesis, diagnosis and management of polymyalgia rheumatica

D Camellino, A Giusti, G Girasole, G Bianchi, C Dejaco - Drugs & Aging, 2019 - Springer
Polymyalgia rheumatica is an inflammatory rheumatic disease of the elderly characterised
by pain and stiffness in the neck and pelvic girdle, and is the second most common …

Whole-body MRI of patients with polymyalgia rheumatica identifies a distinct subset with complete patient-reported response to glucocorticoids

SL Mackie, CT Pease, E Fukuba, E Harris… - Annals of the …, 2015 - ard.bmj.com
Objectives To determine whether whole-body MRI defines clinically relevant subgroups
within polymyalgia rheumatica (PMR) including glucocorticoid responsiveness. Methods 22 …