Exosomes and their role in the life cycle and pathogenesis of RNA viruses

HS Chahar, X Bao, A Casola - Viruses, 2015 - mdpi.com
Exosomes are membrane-enclosed vesicles actively released into the extracellular space,
whose content reflect the physiological/pathological state of the cells they originate from …

A comprehensive insight into the role of exosomes in viral infection: dual faces bearing different functions

MH Saad, R Badierah, EM Redwan, EM El-Fakharany - Pharmaceutics, 2021 - mdpi.com
Extracellular vesicles (EVs) subtype, exosome is an extracellular nano-vesicle that sheds
from cells' surface and originates as intraluminal vesicles during endocytosis. Firstly, it was …

The biology of extracellular vesicles: The known unknowns

L Margolis, Y Sadovsky - PLoS biology, 2019 - journals.plos.org
For many years, double-layer phospholipid membrane vesicles, released by most cells,
were not considered to be of biological significance. This stance has dramatically changed …

A system of cytokines encapsulated in extracellular vesicles

W Fitzgerald, ML Freeman, MM Lederman… - Scientific reports, 2018 - nature.com
Cytokines are soluble factors that mediate cell–cell communications in multicellular
organisms. Recently, another system of cell–cell communication was discovered, which is …

Regulatory T cell-derived extracellular vesicles modify dendritic cell function

SL Tung, DA Boardman, M Sen, M Letizia, Q Peng… - Scientific Reports, 2018 - nature.com
Regulatory T cells (Treg) are a subpopulation of T cells that maintain tolerance to self and
limit other immune responses. They achieve this through different mechanisms including the …

Circulating extracellular vesicles are endowed with enhanced procoagulant activity in SARS-CoV-2 infection

C Balbi, J Burrello, S Bolis, E Lazzarini, V Biemmi… - …, 2021 - thelancet.com
Abstract Background Coronavirus-2 (SARS-CoV-2) infection causes an acute respiratory
syndrome accompanied by multi-organ damage that implicates a prothrombotic state …

Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy

S Chettimada, DR Lorenz, V Misra, ST Dillon… - Scientific reports, 2018 - nature.com
Exosomes are nanovesicles released from most cell types including immune cells. Prior
studies suggest exosomes play a role in HIV pathogenesis, but little is known about …

Exosomes: implications in HIV-1 pathogenesis

MN Madison, CM Okeoma - Viruses, 2015 - mdpi.com
Exosomes are membranous nanovesicles of endocytic origin that carry host and pathogen
derived genomic, proteomic, and lipid cargos. Exosomes are secreted by most cell types into …

Purity and yield of melanoma exosomes are dependent on isolation method

SL Shu, Y Yang, CL Allen, E Hurley… - Journal of …, 2020 - Taylor & Francis
Both exosomes and soluble factors have been implicated in the generation of an
immunosuppressive tumour microenvironment. Determining the contribution of each …

Astrocyte EV-induced lincRNA-Cox2 regulates microglial phagocytosis: implications for morphine-mediated neurodegeneration

G Hu, K Liao, F Niu, L Yang, BW Dallon… - … Therapy-Nucleic Acids, 2018 - cell.com
Impairment of microglial functions, such as phagocytosis and/or dysregulation of immune
responses, has been implicated as an underlying factor involved in the pathogenesis of …