Early developmental conditioning of later health and disease: physiology or pathophysiology?

MA Hanson, PD Gluckman - Physiological reviews, 2014 - journals.physiology.org
Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …

The biology of developmental plasticity and the Predictive Adaptive Response hypothesis

P Bateson, P Gluckman, M Hanson - The Journal of physiology, 2014 - Wiley Online Library
Many forms of developmental plasticity have been observed and these are usually
beneficial to the organism. The Predictive Adaptive Response (PAR) hypothesis refers to a …

Understanding transgenerational epigenetic inheritance via the gametes in mammals

L Daxinger, E Whitelaw - Nature Reviews Genetics, 2012 - nature.com
It is known that information that is not contained in the DNA sequence—epigenetic
information—can be inherited from the parent to the offspring. However, many questions …

Stress exposure, food intake and emotional state

YM Ulrich-Lai, S Fulton, M Wilson, G Petrovich… - Stress, 2015 - Taylor & Francis
This manuscript summarizes the proceedings of the symposium entitled,“Stress, Palatable
Food and Reward”, that was chaired by Drs. Linda Rinaman and Yvonne Ulrich-Lai at the …

Plasticity and robustness in development and evolution

P Bateson, P Gluckman - International Journal of Epidemiology, 2012 - academic.oup.com
Biology presents many wonders, but one of the most remarkable is how a complex
multicellular organism grows from a single cell. Until recently, the processes involved …

[图书][B] Nutrition in the Prevention and Treatment of Disease

CJ Boushey, AM Coulston, CL Rock, E Monsen - 2001 - books.google.com
As we enter the 21st century, a new era of nutrition in the prevention and treatment of
disease emerges. Clinical nutrition involves the integration of diet, genetics, environment …

A unified approach to the evolutionary consequences of genetic and nongenetic inheritance

T Day, R Bonduriansky - The American Naturalist, 2011 - journals.uchicago.edu
Inheritance—the influence of ancestors on the phenotypes of their descendants—translates
natural selection into evolutionary change. For the past century, inheritance has been …

Human transgenerational responses to early-life experience: potential impact on development, health and biomedical research

M Pembrey, R Saffery, LO Bygren - Journal of medical genetics, 2014 - jmg.bmj.com
Mammalian experiments provide clear evidence of male line transgenerational effects on
health and development from paternal or ancestral early-life exposures such as diet or …

Maternal obesity and developmental programming of metabolic disorders in offspring: evidence from animal models

M Li, DM Sloboda, MH Vickers - Journal of Diabetes Research, 2011 - Wiley Online Library
The incidence of obesity and overweight has reached epidemic proportions in the
developed world as well as in those countries transitioning to first world economies, and this …

Assisted reproduction treatment and epigenetic inheritance

APA Van Montfoort, LLP Hanssen… - Human reproduction …, 2012 - academic.oup.com
BACKGROUND The subject of epigenetic risk of assisted reproduction treatment (ART),
initiated by reports on an increase of children with the Beckwith–Wiedemann imprinting …