The OpenGATE ecosystem for Monte Carlo simulation in medical physics

D Sarrut, T Baudier, D Borys, A Etxebeste… - Physics in Medicine …, 2022 - iopscience.iop.org
This paper reviews the ecosystem of GATE, an open-source Monte Carlo toolkit for medical
physics. Based on the shoulders of Geant4, the principal modules (geometry, physics …

A high-granularity digital tracking calorimeter optimized for proton CT

J Alme, GG Barnaföldi, R Barthel, V Borshchov… - Frontiers in …, 2020 - frontiersin.org
A typical proton CT (pCT) detector comprises a tracking system, used to measure the proton
position before and after the imaged object, and an energy/range detector to measure the …

Meeting the detector challenges for pre-clinical proton and ion computed tomography

RP Johnson - Physics in Medicine & Biology, 2024 - iopscience.iop.org
Six decades after its conception, proton computed tomography (pCT) and proton
radiography have yet to be used in medical clinics. However, good progress has been made …

Helium radiography with a digital tracking calorimeter—a Monte Carlo study for secondary track rejection

HES Pettersen, L Volz, JR Sølie, J Alme… - Physics in Medicine …, 2021 - iopscience.iop.org
Radiation therapy using protons and heavier ions is a fast-growing therapeutic option for
cancer patients. A clinical system for particle imaging in particle therapy would enable online …

Investigating particle track topology for range telescopes in particle radiography using convolutional neural networks

HES Pettersen, M Aehle, J Alme, GG Barnaföldi… - Acta …, 2021 - Taylor & Francis
Background Proton computed tomography (pCT) and radiography (pRad) are proposed
modalities for improved treatment plan accuracy and in situ treatment validation in proton …

X-ray CT adaptation based on a 2D–3D deformable image registration framework using simulated in-room proton radiographies

P Palaniappan, S Meyer, M Rädler… - Physics in Medicine …, 2022 - iopscience.iop.org
The aim of this work is to investigate in-room proton radiographies to compensate realistic
rigid and non-rigid transformations in clinical-like scenarios based on 2D–3D deformable …

Theoretical considerations on the spatial resolution limit of single-event particle radiography

L Volz, CA Collins-Fekete, JR Sølie… - Biomedical Physics & …, 2020 - iopscience.iop.org
Particle radiography (pRad) has been proposed and investigated as a promising tool for
particle therapy as it provides a water equivalent thickness (WET) image of the patient. In …

[HTML][HTML] A Monte-Carlo-based study of a single-2D-detector proton-radiography system

F Olivari, MJ van Goethem, S Brandenburg… - Physica Medica, 2023 - Elsevier
Purpose To assess the feasibility of a proton radiography (pRG) system based on a single
thin pixelated detector for water-equivalent path length (WEPL) and relative stopping power …

Development of the trigger-controlling system for the proton computed tomography prototype

N Ritjoho, P Phumara, Y Buanill, P Boontueng… - Nuclear Instruments and …, 2025 - Elsevier
Proton computed tomography (pCT) is an imaging reconstruction technique that uses
protons' positions, directions, and energy loss to generate a map of an object's relative …

Exploration of differentiability in a proton computed tomography simulation framework

M Aehle, J Alme, GG Barnaföldi… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Gradient-based optimization using algorithmic derivatives can be a useful
technique to improve engineering designs with respect to a computer-implemented …