Apoptotic or antiproliferative activity of natural products against keratinocytes for the treatment of psoriasis

TH Huang, CF Lin, A Alalaiwe, SC Yang… - International Journal of …, 2019 - mdpi.com
Natural products or herbs can be used as an effective therapy for treating psoriasis, an
autoimmune skin disease that involves keratinocyte overproliferation. It has been …

Bibliometric study of adaptogens in dermatology: pharmacophylogeny, phytochemistry, and pharmacological mechanisms

XX Liu, CY Chen, L Li, MM Guo, YF He… - Drug Design …, 2023 - Taylor & Francis
Background Adaptogens are a class of medicinal plants that can nonspecifically enhance
human resistance. Most of the plant adaptogens have relevant applications in dermatology …

Role of cellular oxidative stress and cytochrome c in the pathogenesis of psoriasis

SA Gabr, AH Al-Ghadir - Archives of dermatological research, 2012 - Springer
Oxidative-free radicals and apoptosis have linked to chronic skin diseases. Higher levels of
oxidative radicals and the release of mitochondrial cytochrome c may have a role in the …

Topically used herbal products for the treatment of psoriasis–mechanism of action, drug delivery, clinical studies

A Herman, AP Herman - Planta medica, 2016 - thieme-connect.com
Psoriasis is a chronic inflammatory skin disease characterized histologically by
hyperproliferation and aberrant differentiation of epidermal keratinocytes. A wide range of …

Chinese herbal medicine for psoriasis: evidence from 11 high-quality randomized controlled trials

Y Luo, J Chen, L Kuai, Y Zhang, X Ding… - Frontiers in …, 2021 - frontiersin.org
Background: Chinese herbal medicine (CHM) provides a theoretical basis for the treatment
of psoriasis with considerable benefits and a low toxicity. The purpose of this quantitative …

Cryptotanshinone inhibits PFK-mediated aerobic glycolysis by activating AMPK pathway leading to blockade of cutaneous melanoma

Q Chen, Y Liu, Y Zhu, Z Zhu, J Zou, Y Pan, Y Lu… - Chinese Medicine, 2024 - Springer
Background Cutaneous melanoma is a kind of skin malignancy with low morbidity but high
mortality. Cryptotanshinone (CPT), an important component of salvia miltiorrhiza has potent …

Oral C hinese herbal medicine combined with pharmacotherapy for psoriasis vulgaris: a systematic review

CS Zhang, JJ Yu, S Parker, AL Zhang… - International Journal …, 2014 - Wiley Online Library
Clinically, oral C hinese herbal medicine (CHM) is widely used in the treatment of psoriasis.
This review evaluates the effects of oral CHM in combination with pharmacotherapy for …

Research Progress on Regulation of Immune Response by Tanshinones and Salvianolic Acids of Danshen (Salvia miltiorrhiza Bunge)

J Tang, X Zhao - Molecules, 2024 - mdpi.com
As one of the traditional Chinese herbs, Danshen (Salvia miltiorrhiza Bunge) has been
widely studied and widely used in the treatment of cardiovascular, cerebrovascular, and …

Rhodomyrtone as a potential anti-proliferative and apoptosis inducing agent in HaCaT keratinocyte cells

J Chorachoo, D Saeloh, T Srichana, T Amnuaikit… - European Journal of …, 2016 - Elsevier
Psoriasis is a skin disease associated with hyperproliferation and abnormal differentiation of
keratinocytes. Available approaches using synthetic drugs for the treatment of severe …

IFI27, a novel epidermal growth factor‐stabilized protein, is functionally involved in proliferation and cell cycling of human epidermal keratinocytes

WL Hsieh, YH Huang, TM Wang, YC Ming… - Cell …, 2015 - Wiley Online Library
Objectives IFI 27 is highly expressed in psoriatic lesions but its function has not been known.
The present study aimed to explore its role in proliferation of epidermal keratinocytes …