Translocator protein 18 kDa (TSPO) is a transmembrane protein in the mitochondrial
membrane, which has been identified as a peripheral benzodiazepine receptor. TSPO is …

Selenium is one of the eight necessary trace elements humans require for active health
balance. It contributes in several ways to the proper functioning of selenoprotein. Selenium …

We report the first one-pot formal alkene carboradiofluorination reaction employing easily
accessible alkenes as both prosthetic group precursors and coupling partners. The …

There is an unmet need for better therapeutic strategies for advanced prostate cancer. Poly
(ADP-ribose) polymerase-1 (PARP-1) is a chromatin-binding DNA repair enzyme …

BODIPY (4, 4-difluoro-4-bora-3a, 4a-diaza-s-indacene) derivatives have attracted attention
as probes in applications like imaging and sensing due to their unique properties like (1) …

After androgen deprivation therapy, a significant number of prostate cancer cases progress
with a therapy-resistant neuroendocrine phenotype (NEPC). This represents a challenge for …

Antibody drug conjugates (ADCs) have emerged as a new promising class of anti-cancer
agents. However, limitations such as higher costs and unavoidable immunogenicity due to …

Castration-resistant prostate cancer (CRPC) development is the foremost concern after
treatment of patients with high risk with locally advanced or metastatic prostate cancer …

Small molecule toll-like receptor (TLR) 7 agonists have gathered considerable interest as
promising therapeutic agents for applications in cancer immunotherapy. Herein, we describe …

Recently, growing evidence of the relationship between G-protein coupled receptor 44
(GPR44) and the inflammation-cancer system has garnered tremendous interest, while the …