The animal trypanosomiases and their chemotherapy: a review

F Giordani, LJ Morrison, TG Rowan, HP De Koning… - Parasitology, 2016 - cambridge.org
Pathogenic animal trypanosomes affecting livestock have represented a major constraint to
agricultural development in Africa for centuries, and their negative economic impact is …

An update on African trypanocide pharmaceutics and resistance

KI Kasozi, ET MacLeod, I Ntulume… - Frontiers in Veterinary …, 2022 - frontiersin.org
African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

Current treatments to control African trypanosomiasis and one health perspective

A Venturelli, L Tagliazucchi, C Lima, F Venuti… - Microorganisms, 2022 - mdpi.com
Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African
Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same …

The Dermis as a Delivery Site of Trypanosoma brucei for Tsetse Flies

G Caljon, N Van Reet, C De Trez, M Vermeersch… - PLoS …, 2016 - journals.plos.org
Tsetse flies are the sole vectors of Trypanosoma brucei parasites that cause sleeping
sickness. Our knowledge on the early interface between the infective metacyclic forms and …

Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites

M Dawidowski, L Emmanouilidis, VC Kalel… - Science, 2017 - science.org
The parasitic protists of the Trypanosoma genus infect humans and domestic mammals,
causing severe mortality and huge economic losses. The most threatening trypanosomiasis …

Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections

JE Pinto Torres, J Goossens, J Ding, Z Li, S Lu… - Scientific reports, 2018 - nature.com
Animal African trypanosomosis (AAT), a disease affecting livestock, is caused by parasites of
the Trypanosoma genus (mainly T. vivax and T. congolense). AAT is widespread in Sub …

African animal trypanosomiasis: A systematic review on prevalence, risk factors and drug resistance in sub-Saharan Africa

I Okello, E Mafie, G Eastwood… - Journal of medical …, 2022 - academic.oup.com
African animal trypanosomiasis (AAT) a parasitic disease of livestock in sub-Saharan Africa
causing tremendous loses. Sub-Saharan continental estimation of mean prevalence in both …

The potential economic benefits of controlling trypanosomiasis using waterbuck repellent blend in sub-Saharan Africa

Z Abro, M Kassie, B Muriithi, M Okal, D Masiga… - Plos one, 2021 - journals.plos.org
Trypanosomiasis is a significant productivity-limiting livestock disease in sub-Saharan
Africa, contributing to poverty and food insecurity. In this paper, we estimate the potential …

Evidence-based advice on timing and location of tsetse control measures in Shimba Hills National reserve, Kenya

S Gachoki, TA Groen, A Vrieling… - PLoS neglected …, 2023 - journals.plos.org
Controlling tsetse flies is critical for effective management of African trypanosomiasis in Sub-
Saharan Africa. To enhance timely and targeted deployment of tsetse control strategies a …

Development of a rapid antibody test for point-of-care diagnosis of animal African trypanosomosis

A Boulangé, D Pillay, C Chevtzoff, N Biteau… - Veterinary …, 2017 - Elsevier
Trypanosoma congolense and T. vivax are the main causative agents of animal African
trypanosomosis (AAT), a disease which hinders livestock production throughout sub …