Microtubules are dynamic polymers of αβ-tubulin that are essential for intracellular
organization, organelle trafficking and chromosome segregation. Microtubule growth and …

Microtubules have fundamental roles in many essential biological processes, including cell
division and intracellular transport. They assemble and disassemble from their two ends …

Cellular electron cryotomography offers researchers the ability to observe macromolecules
frozen in action in situ, but a primary challenge with this technique is identifying molecular …

Biological systems have evolved to harness non-equilibrium processes from the molecular
to the macro scale. It is currently a grand challenge of chemistry, materials science, and …

Mitotic spindles are self-organizing protein machines that harness teams of multiple force
generators to drive chromosome segregation. Kinesins are key members of these force …

Microtubules are dynamic polymers of αβ-tubulin that form diverse cellular structures, such
as the mitotic spindle for cell division, the backbone of neurons, and axonemes. To control …

Microtubules are cytoskeletal filaments essential for numerous aspects of cell physiology.
They are polarized polymeric tubes with a fast growing plus end and a slow growing minus …

The microtubule (MT) cytoskeleton supports a broad range of cellular functions, from
providing tracks for intracellular transport, to supporting movement of cilia and flagella, to …

Kinesins are a superfamily of microtubule-based ATP-powered motors, important for
multiple, essential cellular functions. How microtubule binding stimulates their ATPase and …

Microtubule organization has a crucial role in regulating cell architecture. The geometry of
microtubule arrays strongly depends on the distribution of sites responsible for microtubule …