One of the hallmarks of stroke pathophysiology is the widespread death of many different
types of brain cells. As our understanding of the complex disease that is stroke has grown, it …

Background and Purpose—The significance of brain temperature to outcome in cerebral
ischemia is recognized. Numerous variations of depth, duration, and delay of cooling have …

An accurate, reproducible method for determining the infarct volumes of gray matter
structures is presented for use with presently available image analysis systems. Areas of …

Infarct volume is one of the common indexes for assessing the extent of ischemic brain injury
following focal cerebral ischemia. Accuracy in the measurement of infarct volume is …

Acute neutrophil (PMN) recruitment to postischemic cardiac or pulmonary tissue has
deleterious effects in the early reperfusion period, but the mechanisms and effects of …

Background Investigations following stroke first of all require information about the spatio-
temporal dimension of the ischemic core as well as of perilesional and remote affected …

Background and Purpose—During focal cerebral ischemia, the ischemic penumbra or
border-zone regions of moderate cortical blood flow reductions have a heterogeneous …

It has become increasingly clear that a stroke lesion usually consists of a densely ischemic
focus and of perifocal areas with better upheld flow rates. At least in rats and cats, some of …

Abstract The cytokine interleukin‐1 (IL‐1) has been implicated in ischaemic, traumatic and
excitotoxic brain damage. The results presented here reveal novel actions of IL‐1 in the …

Background and purpose: 2, 3, 5-Triphenyltetrazolium chloride (TTC) staining measures
tissue viability used to evaluate infarct size. The goal of this study was to compare viability of …