Background: von Willebrand disease (VWD) is the most common inherited bleeding disorder
known in humans. Accurate and timely diagnosis presents numerous challenges. Objective …

Background: von Willebrand disease (VWD) is a common inherited bleeding disorder.
Significant variability exists in management options offered to patients. Objective: These …

Von Willebrand factor (VWF) is a large and complex plasma glycoprotein that is essential for
normal haemostasis. It is well recognized that deficiency of VWF results in a bleeding …

Hemostasis and pathological thrombus formation are dynamic processes that require
multiple adhesive receptor-ligand interactions, with blood platelets at the heart of such …

Normal hemostasis requires von Willebrand factor (VWF) to support platelet adhesion and
aggregation at sites of vascular injury. VWF is a multimeric glycoprotein built from identical …

Von Willebrand disease is a common autosomal inherited bleeding disorder caused by
quantitative or qualitative defects of von Willebrand factor, a multi-adhesive protein that …

Introduction von Willebrand disease (VWD) is one of the most common inherited bleeding
disorders, with a prevalence of symptomatic disease of; 1 in 10 000. Given the complexity of …

Abstract von Willebrand disease (VWD) is the most common autosomally inherited bleeding
disorder. The disease represents a range of quantitative and qualitative pathologies of the …

Platelet function testing is important for the diagnostic evaluation of common and rare
bleeding disorders. Our study goals were to promote best practices and reduce unnecessary …

The common autosomally inherited mucocutaneous bleeding disorder, von Willebrand
disease (VWD) results from quantitative or qualitative defects in plasma von Willebrand …