Towards the sequence‐selective recognition of double‐stranded DNA containing pyrimidine‐purine interruptions by triplex‐forming oligonucleotides

Y Hari, S Obika, T Imanishi - European Journal of Organic …, 2012 - Wiley Online Library
Triplex formation with double‐stranded DNA (dsDNA) by oligonucleotides has potential for
applications in attractive technologies such as gene therapy and genetic diagnosis …

Unnatural nucleosides with unusual base pairing properties

DE Bergstrom - Current Protocols in Nucleic Acid Chemistry, 2009 - Wiley Online Library
Synthetic modified nucleosides designed to pair in unusual ways with natural nucleobases
have many potential applications in biology and biotechnology. This overview lays the …

Synthesis and triplex-forming ability of oligonucleotides bearing 1-substituted 1H-1, 2, 3-triazole nucleobases

Y Hari, M Nakahara, J Pang, M Akabane… - Bioorganic & medicinal …, 2011 - Elsevier
Using the copper (I)-catalyzed alkyne-azide 1, 3-dipolar cycloaddition, a post-elongation
modification of 1-ethynyl substituted nucleobases has been employed to construct 18 …

The Development of Non-natural Type Nucleoside to Stabilize Triplex DNA Formation against CG and TA Inversion Site

L Wang, Y Ling, Y Tian, X Wang… - Current Medicinal …, 2024 - ingentaconnect.com
Based on the sequence-specific recognition of target duplex DNA by triplexforming
oligonucleotides (TFOs) at the major groove side, the antigene strategy has been exploited …

Nucleotides and nucleic acids; oligo-and polynucleotides

D Loakes - 2009 - books.rsc.org
Nucleotides and nucleic acids; oligo- and polynucleotides | Organophosphorus Chemistry |
Books Gateway | Royal Society of Chemistry Skip to Main Content Umbrella Alt Text Umbrella …

Novel nucleotide analogues for forming stable DNA triple helices

SR Gerrard - 2009 - eprints.soton.ac.uk
DNA triple helices are an important tool in a variety of medicinal and biotechnological
applications, such as gene therapy and chemotherapeutics. DNA triple helices are formed …