Several medical management approaches have been shown to be effective in preventing
breast cancer and detecting it early among women at elevated risk: 1) prophylactic …

Over the past several years, there has been an increasing rate of bilateral prophylactic
mastectomy (BPM) and contralateral prophylactic mastectomy (CPM) surgeries. Since …

Chinese translation Background: Rates of contralateral prophylactic mastectomy (CPM)
have increased dramatically, particularly among younger women with breast cancer, but …

Background The equivalency of survival between mastectomy and breast conservation
therapy (BCT) has long been established, resulting in two decades of predominant BCT …

BRCA1/2 mutation carriers with breast cancer are at high risk of contralateral disease. Such
women often elect to have contralateral risk-reducing mastectomy (CRRM) to reduce the …

In recent years, several trials of breast cancer treatment have failed to demonstrate a
survival benefit for some previously routine surgical therapies in selected patient groups. As …

Background The aim of this study was to investigate whether contralateral prophylactic
mastectomy (CPM) in addition to therapeutic mastectomy (TM) is associated with a survival …

Purpose To evaluate the rate of prophylactic contralateral mastectomy in an international
cohort of women with hereditary breast cancer and to evaluate the predictors of uptake of …

Abstract BACKGROUND: For BRCA1/BRCA2 gene testing to benefit public health, mutation
carriers must initiate appropriate risk management strategies. There has been little research …

Importance Rates of bilateral mastectomy continue to increase in average-risk women with
unilateral in situ and invasive breast cancer. Contralateral prophylactic mastectomy rates …