Colon cancer is the third most common cancer worldwide. Most colorectal cancer
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …

Both embryonic and adult stem cells are endowed with a superior capacity to prevent the
accumulation of genetic lesions, repair them, or avoid their propagation to daughter cells …

The cancer stem cell (CSC) theory highlights a self-renewing subpopulation of cancer cells
that fuels tumour growth. The existence of human CSCs is mainly supported by …

Cancer stem cells (CSCs) have been hypothesized to represent the driving force behind
tumour progression and metastasis, making them attractive cancer targets. However …

Diet has a profound effect on tissue regeneration in diverse organisms, and low caloric
states such as intermittent fasting have beneficial effects on organismal health and age …

Epithelial surfaces form critical barriers to the outside world and are continuously renewed
by adult stem cells. Whereas dynamics of epithelial stem cells during homeostasis are …

Renewal of the intestinal epithelium occurs approximately every week and requires a careful
balance between cell proliferation and differentiation to maintain proper lineage ratios and …

The intestinal epithelium is one the fastest renewing tissues in mammals and is endowed
with extensive adaptability. The more traditional view of a hierarchical organization of the gut …

Intermediate filament (IF) proteins make up the largest family of cytoskeletal proteins in
metazoans, and are traditionally known for their roles in fostering structural integrity in cells …

Glioblastoma (GBM), a lethal primary brain tumor, contains glioma stem cells (GSCs) that
promote malignant progression and therapeutic resistance. SOX2 is a core transcription …