Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy: a systematic review and meta-analysis

CJ Wedderburn, E Weldon, C Bertran-Cobo… - The Lancet Child & …, 2022 - thelancet.com
Background There are 15· 4 million children who are HIV-exposed and uninfected
worldwide. Early child development crucially influences later academic and socioeconomic …

Children who are HIV-exposed and uninfected: evidence for action

AJ Prendergast, C Evans - Aids, 2023 - journals.lww.com
Prior to widespread availability of antiretroviral therapy (ART) in sub-Saharan Africa,
children who were HIV-exposed but uninfected (HEU) had increased mortality, morbidity …

Higher prevalence of stunting and poor growth outcomes in HIV-exposed uninfected than HIV-unexposed infants in Kenya

J Neary, A Langat, B Singa, J Kinuthia, J Itindi… - Aids, 2022 - journals.lww.com
Background: With the growing population of HIV-exposed uninfected (HEU) children
globally, it is important to determine population-level growth differences between HEU and …

Lower academic performance among children with perinatal HIV exposure in Botswana

KM Powis, L Lebanna, S Schenkel… - Journal of the …, 2023 - Wiley Online Library
Introduction Studies have reported a higher risk of suboptimal neurodevelopment among
children who are HIV‐exposed uninfected (HEU) compared to children HIV‐unexposed …

Cardio-Metabolic Health of Offspring Exposed in Utero to Human Immuno-Deficiency Virus and Anti-Retroviral Treatment: A Systematic Review

EN Matjuda, GA Engwa, MM Mungamba… - Biology, 2024 - mdpi.com
Simple Summary Although the use of antiretroviral treatment (ART) is effective in reducing
the risk of HIV transmission to the foetus, there are concerns of possible adverse effects of in …

Lower neurocognitive functioning in HIV-exposed uninfected children compared with that in HIV-unexposed children

SF Benki-Nugent, R Yunusa, A Mueni… - JAIDS Journal of …, 2022 - journals.lww.com
Background: Perinatal HIV and antiretroviral therapy exposure may influence neurocognitive
outcomes, although evidence is mixed and most studies are limited to outcomes in the first …

A 12-month prospective study of HIV-infected and HIV-uninfected women and their infants in Malawi: comparative analysis of clinical events and infant growth

M Floridia, S Orlando, M Andreotti… - … American Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Few studies have compared clinical outcomes in HIV-exposed uninfected (HEU) and HIV-
unexposed uninfected (HUU) infants in the current scenario of universal and lifelong …

Growth deficits in antiretroviral and HIV-exposed uninfected versus unexposed children in Malawi and Uganda persist through 60 months of age

MG Fowler, J Aizire, A Sikorskii, P Atuhaire… - Aids, 2022 - journals.lww.com
Objective: To compare childhood physical growth among antiretroviral drug and maternal
HIV-exposed uninfected (AHEU) compared with HIV-unexposed uninfected (HUU) children …

Association of in utero HIV exposure with child brain structure and language development: a South African birth cohort study

CJ Wedderburn, S Yeung, S Subramoney, JP Fouche… - BMC medicine, 2024 - Springer
Background There is a growing population of children with in utero HIV exposure who are at
risk of poor neurodevelopmental outcomes despite avoiding HIV infection. However, the …

Growth faltering and developmental delay in HIV-exposed uninfected Ugandan infants: a prospective cohort study

R Sirajee, AL Conroy, S Namasopo… - JAIDS Journal of …, 2021 - journals.lww.com
Background: HIV-exposed but uninfected (HEU) infants are at increased risk of impaired
early linear growth and cognitive development. We examined associations between …