Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …
consequence of exposure to severe psychological trauma. Although effective treatments …
Inflammation in fear-and anxiety-based disorders: PTSD, GAD, and beyond
The study of inflammation in fear-and anxiety-based disorders has gained interest as
growing literature indicates that pro-inflammatory markers can directly modulate affective …
growing literature indicates that pro-inflammatory markers can directly modulate affective …
LncRNA LINRIS stabilizes IGF2BP2 and promotes the aerobic glycolysis in colorectal cancer
Y Wang, JH Lu, QN Wu, Y Jin, DS Wang, YX Chen… - Molecular cancer, 2019 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) play nonnegligible roles in the
epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that …
epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that …
Imaging the role of inflammation in mood and anxiety-related disorders
JC Felger - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …
and behavior have reported evidence that inflammation and release of inflammatory …
Largest GWAS of PTSD (N= 20 070) yields genetic overlap with schizophrenia and sex differences in heritability
Abstract The Psychiatric Genomics Consortium-Posttraumatic Stress Disorder group (PGC-
PTSD) combined genome-wide case–control molecular genetic data across 11 multiethnic …
PTSD) combined genome-wide case–control molecular genetic data across 11 multiethnic …
Post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) occurs in 5–10% of the population and is twice as
common in women as in men. Although trauma exposure is the precipitating event for PTSD …
common in women as in men. Although trauma exposure is the precipitating event for PTSD …
Meta-analysis of genome-wide association studies of anxiety disorders
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common,
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
Gender-and sex-based contributors to sex differences in PTSD
DM Christiansen, ET Berke - Current psychiatry reports, 2020 - Springer
Abstract Purpose of Review Sex differences in PTSD are well-established with a 2: 1 sex
ratio favouring women. Less well-established is the basis of such differences. The purpose …
ratio favouring women. Less well-established is the basis of such differences. The purpose …
The genetics of stress-related disorders: PTSD, depression, and anxiety disorders
JW Smoller - Neuropsychopharmacology, 2016 - nature.com
Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …
factors: genetic vulnerability and environmental stressors. An important role for …
Genetic variants associated with anxiety and stress-related disorders: a genome-wide association study and mouse-model study
Importance Anxiety and stress-related disorders are among the most common mental
disorders. Although family and twin studies indicate that both genetic and environmental …
disorders. Although family and twin studies indicate that both genetic and environmental …