Energy demand of neurons in brain that is covered by glucose supply from the blood is
ensured by glucose transporters in capillaries and brain cells. In brain, the facilitative …

While modernization has dramatically increased lifespan, it has also witnessed the
increasing prevalence of diseases such as obesity, hypertension, and type 2 diabetes. Such …

Cancer reprogramming is an important facilitator of cancer development and survival, with
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …

An important hallmark in cancer cells is the increase in glucose uptake. GLUT1 is an
important target in cancer treatment because cancer cells upregulate GLUT1, a membrane …

Maintaining blood glucose concentration within a relatively narrow range through periods of
fasting or excess nutrient availability is essential to the survival of the organism. This is …

Malignant cells are known to have accelerated metabolism, high glucose requirements, and
increased glucose uptake. Transport of glucose across the plasma membrane of …

Facilitative glucose transport is mediated by members of the Glut protein family that belong
to a much larger superfamily of 12 transmembrane segment transporters. Six members of …

To develop new and more efficient anti-cancer strategies it will be important to characterize
the products of transcription factor activity essential for tumorigenesis. One such factor is …

In this review we summarize the present state of knowledge of the currently identified
members of the glucose transporter family, propose a basis for their diversity highlighting …

We tested whether the dominant intestinal sugar transporter GLUT2 was inhibited by
intestinal luminal compounds that are inefficiently absorbed and naturally present in foods …