Biochemical and structural insights into 6-phosphogluconate dehydrogenase from Leishmania donovani

P Jakkula, B Narsimulu, IA Qureshi - Applied Microbiology and …, 2021 - Springer
phosphogluconate dehydrogenase (6PGDH) participates in pentose phosphate pathway of
glucose metabolism by catalyzing oxidative decarboxylation of 6-phsophogluconate (6PG) …

Unraveling structural insights of ribokinase from Leishmania donovani

S Gatreddi, V Pillalamarri, D Vasudevan… - International journal of …, 2019 - Elsevier
Ribokinase (RK) is an ATP dependent sugar kinase that enables the entry of ribose in the
metabolism. Leishmania accumulates ribose into the cytosol through hydrolysis of …

Acetylation of sesquiterpenyl epoxy-cyclohexenoids regulates fungal growth, stress resistance, endocytosis, and pathogenicity of nematode-trapping fungus …

YH Chen, LL Zhang, LJ Wang, XT Yue… - Journal of Agricultural …, 2022 - ACS Publications
Sesquiterpenyl epoxy-cyclohexenoids (SECs) that depend on a polyketide synthase–
terpenoid synthase (PKS–TPS) pathway are widely distributed in plant pathogenic fungi …

Influence of 6-aminonicotinamide (6AN) on Leishmania promastigotes evaluated by metabolomics: beyond the pentose phosphate pathway

SH Almugadam, A Trentini, M Maritati, C Contini… - Chemico-biological …, 2018 - Elsevier
Aminonicotinamide (6AN) is an antimetabolite used to inhibit the NADPH-producing pentose
phosphate pathway (PPP) in many cellular systems, making them more susceptible to …