Multiplex immunoassays confer several advantages over widely adopted singleplex
immunoassays including increased efficiency at a reduced expense, greater output per …

Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has continued
development and standardization of methodologies for biomarkers and has provided an …

Summary Background Niemann-Pick disease, type C1 (NPC1) is a lysosomal storage
disorder characterised by progressive neurodegeneration. In preclinical testing, 2 …

Background: Long acting insulin detemir administered intranasally for three weeks
enhanced memory for adults with Alzheimer's disease dementia (AD) or amnestic mild …

Lipids in the brain are major components playing structural functions as well as
physiological roles in nerve cells, such as neural communication, neurogenesis, synaptic …

Alzheimer's disease is a progressive, clinically heterogeneous, and particularly complex
neurodegenerative disease characterized by a decline in cognition. Over the last two …

Alzheimer's disease (AD) is a severe neurodegenerative disorder still in search of effective
methods of diagnosis. Altered levels of the NMDA receptor co-agonist, d-serine, have been …

Introduction This study tested the self‐reported sleep characteristics associated with
cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarkers in cognitively intact older …

Objective To determine whether the extent of overlap of the genetic architecture among the
sporadic late-onset Alzheimer's Disease (sLOAD), familial late-onset AD (fLOAD), sporadic …

Background Neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's
disease with dementia (PDD), and dementia with Lewy bodies (DLB) share clinical and …