Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories
Single-cell RNA sequencing (scRNA-seq) is a widely used method for identifying cell types
and trajectories in biologically heterogeneous samples, but it is limited in its detection and …
and trajectories in biologically heterogeneous samples, but it is limited in its detection and …
Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome
Trisomy of human chromosome 21 (Down syndrome, DS) alters development of multiple
organ systems, including the face and underlying skeleton. Besides causing stigmata, these …
organ systems, including the face and underlying skeleton. Besides causing stigmata, these …
Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders
The chromodomain family member chromodomain 1 (CHD1) has been shown to have
numerous critical molecular functions including transcriptional regulation, splicing, and DNA …
numerous critical molecular functions including transcriptional regulation, splicing, and DNA …
[HTML][HTML] E-liquids and vanillin flavoring disrupts retinoic acid signaling and causes craniofacial defects in Xenopus embryos
Environmental teratogens such as smoking are known risk factors for developmental
disorders such as cleft palate. While smoking rates have declined, a new type of smoking …
disorders such as cleft palate. While smoking rates have declined, a new type of smoking …
Retinoid-X receptor agonists increase thyroid hormone competence in lower jaw remodeling of pre-metamorphic Xenopus laevis tadpoles
BJ Mengeling, LF Vetter, JD Furlow - PloS one, 2022 - journals.plos.org
Thyroid hormone (TH) signaling plays critical roles during vertebrate development, including
regulation of skeletal and cartilage growth. TH acts through its receptors (TRs), nuclear …
regulation of skeletal and cartilage growth. TH acts through its receptors (TRs), nuclear …
Uncovering the Pathogenesis of Orofacial Clefts Using Bioinformatics Analysis
X Dong, T Meng, L Lei - Journal of Craniofacial Surgery, 2022 - journals.lww.com
Objective: Many genes have been found to be associated with the occurrence of the
orofacial clefts (OFC). The links between these pathogenic genes are rarely studied. In this …
orofacial clefts (OFC). The links between these pathogenic genes are rarely studied. In this …
[引用][C] Rethinking retinoic acid self-regulation: A signaling robustness network approach
A Fainsod, R Vadigepalli - 2024 - Elsevier