Circular RNAs (circRNAs) are a class of noncoding RNAs with a covalently closed loop
structure. Recent evidence has shown that circRNAs can regulate gene transcription …

Amyl nitrite was introduced in 1867 as the first molecule of a new class of agents for the
treatment of angina pectoris. In the following 150 years, the nitric oxide pathway has been …

BACKGROUND: The laser Doppler fluxmetry (LDF) is a non-invasive method to assess skin
blood perfusion, measuring the flow of blood cells inside a tissue volume without harming …

Objective To investigate the effects of thyroid-stimulating hormone (TSH) on the expression
of endothelial nitric oxide synthase (eNOS) in human microvascular endothelial cells (HMEC …

Peripheral artery disease (PAD) is a highly prevalent disorder with a high risk of mortality
and amputation despite the introduction of novel medical and procedural treatments …

Objective: The aim of this long-term follow-up study was to investigate the association of
local and systemic cardiovascular complications with endothelium-dependent and …

Background The role of cutaneous microvascular dysfunction is well known in the
development of chronic venous disease. However, the effects of venous obstruction on …

Pharmacokinetic Properties using Graph-Based Signatures). Os parâmetros físicoquímicos
e a predição ADMET sugeriram que o NDIBP apresentou boa biodisponibilidade oral …

RESUMO PALMA, Rosana da Silva Costa. Avaliação de mediadores inflamatórios e fatores
de crescimento associados à disfunção endotelial nas manifestações clínicas da doença …