The vitamin D receptor (VDR) belongs to the nuclear receptor superfamily of transcription
factors. The VDR is expressed in diverse brain regions and has been implicated in the …

In addition to its role in calcium homeostasis and bone formation, a modulatory role of the
active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been …

Vitamin D and its metabolites have pleomorphic roles in both nervous system health and
disease. Animal models have been paramount in contributing to our knowledge and …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

It has been known for more than 20 years that vitamin D exerts marked effects on immune
and neural cells. These non-classical actions of vitamin D have recently gained a renewed …

Since its discovery during the epidemic of rickets in the early 1920s, the physiological effects
of vitamin D on calcium/phosphorus homeostasis have been thoroughly studied. Along with …

Vitamin D insufficiency is common in the United States; the elderly and African‐Americans
are at particularly high risk of deficiency. This review, written for a broad scientific …

A role for vitamin D in brain development and function has been gaining support over the
last decade. Multiple lines of evidence suggest that this vitamin is actually a neuroactive …

Background Vitamin D deficiency has been implicated as a risk factor for dementia in
several cross-sectional studies. We tested the hypothesis that reduced plasma 25 …

Background Hypovitaminosis D, a condition that is highly prevalent in older adults aged 65
years and above, is associated with brain changes and dementia. Given the rapidly …