ABSTRACT Introduction Matrix metalloproteinases (MMPs) are a group of enzymes that are
essential in maintaining extracellular matrix (ECM) homeostasis, regulating inflammation …

Amniotic fluid is a complex biological medium that offers protection to the fetus and plays a
key role in normal fetal nutrition, organogenesis, and potentially fetal programming. Amniotic …

Rhinosinusitis (RS) is an acute (ARS) or chronic (CRS) inflammatory disease of the nasal
and paranasal sinus mucosa. CRS is a heterogeneous condition characterized by distinct …

Oral squamous cell carcinoma (OSCC) is one of the most frequent types of head and neck
cancer. Despite the genetic and environmental risk factors, OSCC is also associated with …

Purpose The purpose of this study was to analyze the nasal lymphatic system in order to
uncover novel factors that might be involved in pathogenesis of chronic rhinosinusitis (CRS) …

Chronic rhinosinusitis with nasal polyp (CRSwNP) is a highly prevalent disorder
characterized by persistent nasal and sinus mucosa inflammation. Despite significant …

Clusterin has the potential to become the biomarker of multiple diseases, but its clinical
quantitative detection methods are limited, which restricts its research progress as a …

Introduction The end of gestation, ensuing parturition, and the neonatal period represent
highly dynamic phases for immunological changes in both mother and offspring. The …

Background: Chronic rhinosinusitis is classified into eosinophilic chronic rhinosinusitis
(ECRS) and non-eosinophilic chronic rhinosinusitis (NECRS). ECRS is a refractory allergic …

Objective To investigate the role of S100A8 in chronic rhinosinusitis with nasal polyps
(CRSwNP) and assess its value in predicting disease recurrence after surgery. Methods …