Melioidosis: evolving concepts in epidemiology, pathogenesis, and treatment

BJ Currie - Seminars in respiratory and critical care medicine, 2015 - thieme-connect.com
Infection with Burkholderia pseudomallei can result in asymptomatic seroconversion, a
single skin lesion that may or may not heal spontaneously, a pneumonia which can be …

Human melioidosis

I Gassiep, M Armstrong, R Norton - Clinical microbiology reviews, 2020 - Am Soc Microbiol
The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …

Melioidosis: clinical impact and public health threat in the tropics

R Perumal Samy, BG Stiles, G Sethi… - PLoS neglected tropical …, 2017 - journals.plos.org
This review briefly summarizes the geographical distribution and clinical impact of
melioidosis, especially in the tropics. Burkholderia pseudomallei (a gram-negative …

[HTML][HTML] Human melioidosis caused by novel transmission of Burkholderia pseudomallei from freshwater home aquarium, United States

P Dawson, MM Duwell, MG Elrod… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
Nearly all cases of melioidosis in the continental United States are related to international
travel to areas to which Burkholderia pseudomallei, the bacterium that causes melioidosis, is …

[HTML][HTML] A review of melioidosis cases in the Americas

TJ Benoit, DD Blaney, TJ Doker, JE Gee… - The American journal …, 2015 - ncbi.nlm.nih.gov
Melioidosis is a bacterial infection caused by Burkholderia pseudomallei, a gram-negative
saprophytic bacillus. Cases occur sporadically in the Americas with an increasing number of …

Airborne Transmission of Melioidosis to Humans from Environmental Aerosols Contaminated with B. pseudomallei

PS Chen, YS Chen, HH Lin, PJ Liu, WF Ni… - PLoS neglected …, 2015 - journals.plos.org
Melioidosis results from an infection with the soil-borne pathogen Burkholderia
pseudomallei, and cases of melioidosis usually cluster after rains or a typhoon. In an …

Layered and integrated medical countermeasures against Burkholderia pseudomallei infections in C57BL/6 mice

CP Klimko, JL Shoe, NO Rill, M Hunter… - Frontiers in …, 2022 - frontiersin.org
Burkholderia pseudomallei, the gram-negative bacterium that causes melioidosis, is
notoriously difficult to treat with antibiotics. A significant effort has focused on identifying …

Phylogenomic analysis reveals an Asian origin for African Burkholderia pseudomallei and further supports melioidosis endemicity in Africa

DS Sarovich, B Garin, B De Smet, M Kaestli, M Mayo… - MSphere, 2016 - Am Soc Microbiol
Burkholderia pseudomallei, an environmental bacterium that causes the deadly disease
melioidosis, is endemic in northern Australia and Southeast Asia. An increasing number of …

Burkholderia pseudomallei, the causative agent of melioidosis, is rare but ecologically established and widely dispersed in the environment in Puerto Rico

CM Hall, S Jaramillo, R Jimenez… - PLoS neglected …, 2019 - journals.plos.org
Background Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent
of melioidosis. The global burden and distribution of melioidosis is poorly understood …

Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei: Deviation from the Norm

NL Podnecky, KA Rhodes, T Mima, HR Drew… - MBio, 2017 - Am Soc Microbiol
The trimethoprim and sulfamethoxazole combination, co-trimoxazole, plays a vital role in the
treatment of Burkholderia pseudomallei infections. Previous studies demonstrated that the B …