Ullmann‐Goldberg and Buchwald‐Hartwig C− N Cross Couplings: Synthetic Methods to Pharmaceutically Potential N‐Heterocycles
B Seifinoferest, A Tanbakouchian… - Asian Journal of …, 2021 - Wiley Online Library
Abstract The Carbon‐Nitrogen bond formation has always been an important and useful tool
in drug discovery. Its wide applications in synthesizing N‐heterocycles, known as the most …
in drug discovery. Its wide applications in synthesizing N‐heterocycles, known as the most …
Deciphering the key heterocyclic scaffolds in targeting microtubules, kinases and carbonic anhydrases for cancer drug development
MN Peerzada, E Hamel, R Bai, CT Supuran… - Pharmacology & …, 2021 - Elsevier
Heterocyclic scaffolds are widely utilized for drug design by taking into account the
molecular structure of therapeutic targets that are related to a broad spectrum of ailments …
molecular structure of therapeutic targets that are related to a broad spectrum of ailments …
Synthesis of pyrido-fused quinazolinone derivatives via copper-catalyzed domino reaction
M Liu, M Shu, C Yao, G Yin, D Wang, J Huang - Organic letters, 2016 - ACS Publications
A simple and efficient synthesis of 11 H-pyrido [2, 1-b] quinazolin-11-ones by Cu (OAc) 2·
H2O-catalyzed reaction of easily available substituted isatins and 2-bromopyridine …
H2O-catalyzed reaction of easily available substituted isatins and 2-bromopyridine …
Base‐controlled selectivity in the synthesis of linear and angular fused quinazolinones by a palladium‐catalyzed carbonylation/nucleophilic aromatic substitution …
J Chen, K Natte, A Spannenberg… - Angewandte Chemie …, 2014 - Wiley Online Library
A new approach for the facile synthesis of fused quinazolinone scaffolds through a
palladium‐catalyzed carbonylative coupling followed by an intramolecular nucleophilic …
palladium‐catalyzed carbonylative coupling followed by an intramolecular nucleophilic …
Recent advances in the tandem copper-catalyzed Ullmann–Goldberg N-arylation–cyclization strategies
JM Honnanayakanavar, O Obulesu… - Organic & Biomolecular …, 2022 - pubs.rsc.org
N–Aryl bond formation under copper catalysis has played a pivotal role and has been
extensively used as a key step in the total syntheses of several therapeutic molecules. The …
extensively used as a key step in the total syntheses of several therapeutic molecules. The …
Cobalt (III)-Catalyzed Oxadiazole-Directed C–H Activation for the Synthesis of 1-Aminoisoquinolines
F Yang, J Yu, Y Liu, J Zhu - Organic letters, 2017 - ACS Publications
Aromatic heterocycles have been identified as effective directing groups (DGs) in C–H
functionalization but can be retained as undesired bulky substituents in the final products …
functionalization but can be retained as undesired bulky substituents in the final products …
Synthesis of Pyrido[2,1-b]quinazolin-11-ones and Dipyrido[1,2-a:2′,3′-d]pyrimidin-5-ones by Pd/DIBPP-Catalyzed Dearomatizing Carbonylation
T Xu, H Alper - Organic letters, 2015 - ACS Publications
N-Fused heterocycles can be easily synthesized by palladium-catalyzed dearomatizing
carbonylation using 1, 3-bis (diisobutylphosphino) propane (DIBPP) as the ligand. Pyrido [2 …
carbonylation using 1, 3-bis (diisobutylphosphino) propane (DIBPP) as the ligand. Pyrido [2 …
Design, synthesis, molecular modeling, and biological evaluation of novel α-aminophosphonates based quinazolinone moiety as potential anticancer agents: DFT …
Abstract Diphenyl (aryl)(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acid hydrazino methyl
phosphonate (IIIa-k) was achieved upon the reaction of 3, 4-dihydro-(4-oxo-2-phenyl-4H …
phosphonate (IIIa-k) was achieved upon the reaction of 3, 4-dihydro-(4-oxo-2-phenyl-4H …
[HTML][HTML] A binuclear aluminium complex as a single competent catalyst for efficient synthesis of urea, biuret, isourea, isothiourea, phosphorylguanidine, and …
The synthesis and characterisation of two mononuclear aluminium alkyl complexes with the
general composition [Al (Me) 2 {Ph2P (E) N (CH2) 2N (CH2CH2) 2O}](E= Se (2a); S (2b)) …
general composition [Al (Me) 2 {Ph2P (E) N (CH2) 2N (CH2CH2) 2O}](E= Se (2a); S (2b)) …
Copper‐Catalyzed Aerobic Oxidative Annulation and Carbon‐Carbon Bond Cleavage of Arylacetamides: Domino Synthesis of Fused Quinazolinones
J Sun, Q Tan, W Yang, B Liu… - Advanced Synthesis & …, 2014 - Wiley Online Library
An efficient copper‐catalyzed tandem aerobic oxidative annulation and carbon‐carbon bond
cleavage reaction was developed from easily accessible arylacetamides, which provides a …
cleavage reaction was developed from easily accessible arylacetamides, which provides a …