Epidermal growth factor receptor inhibitors as potential anticancer agents: An update of recent progress
Epidermal growth factor receptor (EGFR) is a vital intermediate in cell signaling pathway
including cell proliferation, angiogenesis, apoptosis, and metastatic spread and also having …
including cell proliferation, angiogenesis, apoptosis, and metastatic spread and also having …
Nitrogen‐Containing Heterocyclic Scaffolds as EGFR Inhibitors: Design Approaches, Molecular Docking, and Structure‐Activity Relationships
Cancer is a wide collection of diseases and among the numerous pathways involved in
cancer pathogenesis, pathway involving epidermal growth factor receptor (EGFR) is one of …
cancer pathogenesis, pathway involving epidermal growth factor receptor (EGFR) is one of …
New oxadiazole and pyrazoline derivatives as anti-proliferative agents targeting EGFR-TK: design, synthesis, biological evaluation and molecular docking study
Two new series of oxadiazole and pyrazoline derivatives were designed and synthesized as
promising EGFR-TK inhibitors. The in vitro antiproliferative activity was studied against three …
promising EGFR-TK inhibitors. The in vitro antiproliferative activity was studied against three …
Comparison of various synthesis methods and synthesis parameters of pyrazoline derivates
Pyrazoline plays an important role in the development of heterocyclic chemistry theory and
is widely used as a synthesis useful in organic synthesis. The structure of the pyrazoline …
is widely used as a synthesis useful in organic synthesis. The structure of the pyrazoline …
Novel benzothiazole–pyrazoline–styrene hybrid for ultrasensitive detection of Hg (II) ions: Synthesis and chemosensor evaluation
Water pollution has become a serious issue, and mercury (II) ion (Hg (II)) is highly toxic even
at low concentrations. Therefore, Hg (II) concentration should be strictly monitored. This …
at low concentrations. Therefore, Hg (II) concentration should be strictly monitored. This …
[PDF][PDF] Virtual screening of anticancer activity of chalcones and pyrazolines as potential EGFR, VEGFR, and cytochrome P450 inhibitors
HL Wiraswati, MH Bashari… - J Pharm …, 2023 - pdfs.semanticscholar.org
Context: Metastatic breast cancer is still categorized as an incurable disease because all
available therapies are palliative treatments to relieve symptoms and increase life …
available therapies are palliative treatments to relieve symptoms and increase life …
Evaluation of the anticancer activity of hydroxyxanthones against human liver carcinoma cell line
YS Kurniawan, N Fatmasari, J Jumina… - Journal of …, 2024 - pandawainstitute.com
Nowadays, cancer is one of the most fatal diseases in developed and developing countries.
Therefore, it is an urgent need to find more effective anticancer drugs among the recent …
Therefore, it is an urgent need to find more effective anticancer drugs among the recent …
Molecular Docking Approach For Design and Synthesis of Thioxanthone Derivatives as Anticancer Agents
Thioxanthone derivatives were docked, synthesized, and tested for their anticancer activity.
The molecular docking results showed that 1‐hydroxythioxanthone, 2‐chloro‐1 …
The molecular docking results showed that 1‐hydroxythioxanthone, 2‐chloro‐1 …
A mini-review on pyrazolines as fluorescent chemosensors for Fe3+
Pyrazoline derivatives exhibit potential application as sensitive and selective chemosensors
for the recognition of Fe3+ ions. Their distinctive structure has both donating and accepting …
for the recognition of Fe3+ ions. Their distinctive structure has both donating and accepting …
Synthesis, antimalarial activity assay and molecular docking study of N-substituted chloro-pyrazolines
Purpose: To synthesize chloro-pyrazolines (A–D), determine their antimalarial activity
against Plasmodium falciparum strain 3D7 in vitro, and understand the interaction between …
against Plasmodium falciparum strain 3D7 in vitro, and understand the interaction between …