Niosomal drug delivery for transdermal targeting: recent advances

R Muzzalupo, L Tavano - … and reports in transdermal drug delivery, 2015 - Taylor & Francis
Niosomes are vesicular nanocarriers and are receiving much attention as potential
transdermal drug delivery systems due to properties such as enhanced drug penetration …

Proniosomes derived niosomes: recent advancements in drug delivery and targeting

M Khatoon, KU Shah, FU Din, SU Shah… - Drug …, 2017 - Taylor & Francis
Vesicular drug delivery systems have gained wide attention in the field of nanotechnology.
Among them proniosomes become the superior over other vesicular carriers. Proniosomes …

pH-responsive chitosan-adorned niosome nanocarriers for co-delivery of drugs for breast cancer therapy

S Karimifard, N Rezaei, E Jamshidifar… - ACS Applied Nano …, 2022 - ACS Publications
Breast cancer incidence has increased in recent decades. In the present study, an optimum
formulation of chitosan (CS)-adorned niosome-based nanocarriers for co-delivery of …

Cellular uptake, cytotoxicity and in-vivo evaluation of Tamoxifen citrate loaded niosomes

DS Shaker, MA Shaker, MS Hanafy - International journal of pharmaceutics, 2015 - Elsevier
One of the main challenges in Tamoxifen cancer therapy is achieving localized, efficient and
sustained delivery without harming normal healthy organs. This study focused on evaluating …

Optimization, physicochemical characterization, and antimicrobial activity of a novel simvastatin nano-niosomal gel against E. coli and S. aureus

I Akbarzadeh, M Keramati, A Azadi, E Afzali… - Chemistry and Physics …, 2021 - Elsevier
Niosomes, as a kind of drug delivery system, is widely used for the topical delivery of
lipophilic drugs. Optimization of niosomes plays an essential role in enhancing their …

Fabrication and appraisal of simvastatin via tailored niosomal nanovesicles for transdermal delivery enhancement: In vitro and in vivo assessment

HF Salem, RM Kharshoum, HA Abou-Taleb, HO Farouk… - Pharmaceutics, 2021 - mdpi.com
Simvastatin (SIM) is a HMG-CoA reductase inhibitor employed in the management of
hyperlipidemia. However, its low bioavailability limits its clinical efficacy. The objective of this …

Co-delivery of doxorubicin and paclitaxel via noisome nanocarriers attenuates cancerous phenotypes in gastric cancer cells

N Rezaei, MK Arki, Z Miri-Lavasani, R Solhi… - European Journal of …, 2023 - Elsevier
Gastric cancer (GC) is known as a deadly malignancy all over the world, yet none of the
current therapeutic regimens have achieved efficacy. this current study has aimed to …

Ex vivo permeation parameters and skin deposition of melatonin-loaded microemulsion for treatment of alopecia

AA Elshall, AM Ghoneim, HM Abdel-Mageed… - Future Journal of …, 2022 - Springer
Background Melatonin (MEL) is a powerful antioxidant molecule with anti-androgenic
property. A microemulsion (ME) system loaded with MEL was designed for treatment of …

Optimization of transdermal atorvastatin calcium–Loaded proniosomes: Restoring lipid profile and alleviating hepatotoxicity in poloxamer 407-induced hyperlipidemia

YA Eltellawy, M El-Kayal, RF Abdel-Rahman… - International Journal of …, 2021 - Elsevier
In an attempt to optimize the anti-hyperlipidemic effect and reduce statins induced
hepatotoxicity, Atorvastatin Calcium (ATC) transdermal proniosomal gel (PNG) was …

Fabrication and Assessment of Orodispersible Tablets Loaded with Cubosomes for the Improved Anticancer Activity of Simvastatin against the MDA-MB-231 Breast …

RM Zaki, A El Sayeh Abou El Ela, AS Almurshedi… - Polymers, 2023 - mdpi.com
Various factors limit the use of simvastatin as an anticancer drug. Therefore, this study aimed
to analyse simvastatin (SIM)-loaded cubosome efficacy against breast cancer. SIM-loaded …