Traditional views of cellular metabolism imply that it is passively adapted to meet the
demands of the cell. It is becoming increasingly clear, however, that metabolites do more …

Cancer cells acquire distinct metabolic preferences based on their tissue of origin, genetic
alterations and degree of interaction with systemic hormones and metabolites. These …

Chronic diseases represent a major challenge in world health. Metabolic syndrome is a
constellation of disturbances affecting several organs, and it has been proposed to be a liver …

Diet is frequently considered as a food regimen focused on weight loss, while it is actually
the sum of food consumed by the organism. Western diets, modern lifestyle, sedentary …

Ketogenic diets (KDs) have gained popularity among patients and researchers alike due to
their putative anti-tumor mechanisms. However, the question remains which conclusions …

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor worldwide;
however, the traditional therapeutic approaches and survival rates are still limited. To …

In this work, we investigated the ameliorative effects of platycodin D (PD), a major active
chemical ingredient isolated from the roots of Platycodon grandiflorum (PG), on high-fat diet …

The metabolic pathway of de novo lipogenesis is frequently upregulated in human liver
tumours, and its upregulation is associated with poor prognosis. Blocking lipogenesis in …

Over the last few years, the complexity and diversity of gut microbiota within and across
individuals has been detailed in relation to human health. Further, understanding of the …

Abstract Ethnopharmacological relevance Gynura procumbens (Lour.) Merr,(Family
Asteraceae), which serves as both medicine and food in traditional ethnic medicine, has the …