Adult stem cells are fundamental to maintain tissue homeostasis, growth, and regeneration.
They reside in specialized environments called niches. Following activating signals, they …

The prospects of achieving regeneration in the central nervous system (CNS) have
changed, as most recent findings indicate that several species, including humans, can …

Blood coagulation factors and other proteins, with modulatory effects or modulated by the
coagulation cascade have been reported to affect the pathophysiology of the central …

Olfactory ensheathing glial cells (OECs) are a specialized type of glia that form a
continuously aligned cellular pathway that actively supports unprecedented regeneration of …

Spinal cord injury (SCI) is a devastating type of neurological disorder of the central nervous
system (CNS) with high mortality and disability. The pathological processes of SCI can …

Background Plasminogen activator inhibitor type 1 (PAI-1) is the primary inhibitor of
urokinase type plasminogen activators (uPA) and tissue type plasminogen activators (tPA) …

Spinal cord injury (SCI) is generally the consequence of physical damage, which may result
in devastating consequences such as paraplegia or paralysis. Some certain candidates for …

One of the promising strategies for neural repair therapies is the transplantation of olfactory
ensheathing cells (OECs) which are the glial cells of the olfactory system. We evaluated the …

A key role of both coagulation and vascular thrombosis has been reported since the first
descriptions of multiple sclerosis (MS). Subsequently, the observation of a close …

Stem cell transplantation is a promising therapeutic strategy to enhance axonal regeneration
after spinal cord injury. Unrestricted somatic stem cells (USSC) isolated from human …