Stroke is the fifth leading cause of death in the US, with more than 100,000 deaths annually.
There are a multitude of risks associated with stroke, including aging, cardiovascular …

Since most patients with metastatic castration-resistant prostate cancer (mCRPC) have bone
metastases, it is important to understand the potential impact of therapies on prognostic …

Purpose: Radium-223 prolongs survival in a fraction of men with bone metastatic prostate
cancer (PCa). However, there are no markers for monitoring response and resistance to …

Prostate cancer (PCa) is the most frequent cancer in men aged 65 and over. PCa mainly
metastasizes in the bone, forming osteosclerotic lesions, inducing pain, fractures, and nerve …

A peptide-modified gold nanoparticle was developed for tumour-targeted therapy. Triggered
by alkaline phosphatase, the CREKA-YPFFK (Nph) peptide can self-assemble and further …

Background Many studies have evaluated the relationship between alkaline phosphatase
(ALP) and the prognosis for prostate cancer (PCa). But they have not reached a widespread …

Background Diagnosis of metastatic castrate resistant prostate cancer (mCRPC) with current
biomarkers is difficult and often results in unnecessary invasive procedures as well as over …

Introduction: Among several genetic alterations involved in the progression of prostate
cancer, B cell lymphoma gene number 2 (BCL-2) is an important target molecule in the …

Alkaline phosphatase (ALP), a homo‐dimeric enzyme has been widely used in various
bioassays as disease markers and enzyme probes. Recent advancements of digital …

OBJECTIVE: The aim of the study was to analyze the clinical data of newly diagnosed
prostate cancer (PCa) patients with bone metastasis and to explore the relevant risk factors …