Faecal incontinence, which is defined by the unintentional loss of solid or liquid stool, has a
worldwide prevalence of≤ 7% in community-dwelling adults and can markedly impair …

The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

We report the first study assessing human colon manometric features and their correlations
with changes in autonomic functioning in patients with refractory chronic constipation prior to …

Background Conformal sphincter preservation operation (CSPO) is a new surgical
procedure for very low rectal cancers (within 4–5 cm from the anal verge). CSPO preserves …

Aim The internal anal sphincter (IAS) contributes substantially to anorectal functions. While
its autonomic nerve supply has been studied at the microscopic level, little information is …

Detailed knowledge of the anatomy of the rhabdosphincter and adjacent tissues is
mandatory during urologic surgery to ensure reliable oncologic and functional outcomes. To …

Purpose Sparing the extrinsic autonomic innervation of the internal anal sphincter during
total mesorectal excision is important for the preservation of anal sphincter function. This …

Aims To characterize the nature and function of the levator ani muscle innervation pathways
and to perform a comprehensive three‐dimensional reconstruction of female pelvic …

Purpose Fecal incontinence is a common problem after anal sphincter-preserving
operations. The intersphincteric autonomic nerves supplying the internal anal sphincter …

Purpose Nerves serving the internal anal sphincter (NIAS) have been described as the
lower rectal branches of the pelvic autonomic nerve plexus. However, their topographical …