Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula

L Zhao, H Zhang, N Li, J Chen, H Xu, Y Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …

Network pharmacology approach for medicinal plants: review and assessment

F Noor, M Tahir ul Qamar, UA Ashfaq, A Albutti… - Pharmaceuticals, 2022 - mdpi.com
Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …

TCM network pharmacology: a new trend towards combining computational, experimental and clinical approaches

W Xin, W Zi-Yi, JH Zheng, LI Shao - Chinese journal of natural medicines, 2021 - Elsevier
Traditional Chinese medicine (TCM) is a precious treasure of the Chinese nation and has
unique advantages in the prevention and treatment of diseases. The holistic view of TCM …

HERB: a high-throughput experiment-and reference-guided database of traditional Chinese medicine

SS Fang, L Dong, L Liu, JC Guo, LH Zhao… - Nucleic acids …, 2021 - academic.oup.com
Pharmacotranscriptomics has become a powerful approach for evaluating the therapeutic
efficacy of drugs and discovering new drug targets. Recently, studies of traditional Chinese …

COCONUT online: collection of open natural products database

M Sorokina, P Merseburger, K Rajan, MA Yirik… - Journal of …, 2021 - Springer
Natural products (NPs) are small molecules produced by living organisms with potential
applications in pharmacology and other industries as many of them are bioactive. This …

Network pharmacology databases for traditional Chinese medicine: review and assessment

R Zhang, X Zhu, H Bai, K Ning - Frontiers in pharmacology, 2019 - frontiersin.org
The research field of systems biology has greatly advanced and, as a result, the concept of
network pharmacology has been developed. This advancement, in turn, has shifted the …

Network pharmacology approaches for research of Traditional Chinese Medicines

LI Xiang, LIU Ziqi, L Jie, C Qian, LU Xiaoyan… - Chinese Journal of …, 2023 - Elsevier
Pharmacodynamics material basis and effective mechanisms are the two main issues to
decipher the mechnisms of action of Traditional Chinese medicines (TCMs) for the treatment …

Review on natural products databases: where to find data in 2020

M Sorokina, C Steinbeck - Journal of cheminformatics, 2020 - Springer
Natural products (NPs) have been the centre of attention of the scientific community in the
last decencies and the interest around them continues to grow incessantly. As a …

ETCM: an encyclopaedia of traditional Chinese medicine

HY Xu, YQ Zhang, ZM Liu, T Chen, CY Lv… - Nucleic acids …, 2019 - academic.oup.com
Traditional Chinese medicine (TCM) is not only an effective solution for primary health care,
but also a great resource for drug innovation and discovery. To meet the increasing needs …

SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping

Y Wu, F Zhang, K Yang, S Fang, D Bu, H Li… - Nucleic acids …, 2019 - academic.oup.com
Recently, the pharmaceutical industry has heavily emphasized phenotypic drug discovery
(PDD), which relies primarily on knowledge about phenotype changes associated with …