Tumor-associated macrophages (TAMs) are major innate immune cells that constitute up to
50% of the cell mass of human tumors. TAMs are highly heterogeneous cells that originate …

Despite the high long-term survival in localized prostate cancer, metastatic prostate cancer
remains largely incurable even after intensive multimodal therapy. The lethality of advanced …

Background Prostate cancer (PCa) is one of the most frequently diagnosed cancers in the
world. Emerging evidence suggests that inflammatory cells such as M2 macrophages and …

Tumor‐associated macrophages (TAMs) play a pivotal role in tumor growth in human
malignancies. Published studies have analyzed the relationship between TAM infiltration …

Macrophages are phagocytic sentinel cells of the immune system that are central to both
innate and adaptive immune responses and serve as the first line of defense against …

It is becoming increasingly clear that inflammation influences prostate cancer (PCa)
development and that immune cells are among the primary drivers of this effect. This …

The majority of basic and clinical studies have shown a protumor function of tumor‐
associated macrophages (TAMs), which represent a large proportion of matrix cells. TAMs …

Improved risk stratification is needed for patients with localized prostate cancer. This study
characterized and assessed the prognostic potential of distinct immune cell infiltration …

Cancer cells all share the feature of being immersed in a complex environment with altered
cell-cell/cell-extracellular element communication, physicochemical information, and tissue …

The morbidity of prostate cancer (PCa) is rising year by year, and it has become the primary
cause of tumor‐related mortality in males. It is widely accepted that macrophages account …