Formulation strategies for enhancing the bioavailability of silymarin: the state of the art

A Di Costanzo, R Angelico - Molecules, 2019 - mdpi.com
Silymarin, a mixture of flavonolignan and flavonoid polyphenolic compounds extractable
from milk thistle (Silybum marianum) seeds, has anti-oxidant, anti-inflammatory, anti-cancer …

Recent advances in the analysis of flavonolignans of Silybum marianum

D Csupor, A Csorba, J Hohmann - Journal of pharmaceutical and …, 2016 - Elsevier
Extracts of milk thistle (Silybum marianum, Asteraceae) have been recognized for centuries
as remedies for liver and gallbladder disorders. The active constituents of milk thistle fruits …

[HTML][HTML] Sequential selective supercritical fluid extraction (S3FE) of triglycerides and flavonolignans from milk thistle (Silybum marianum L, Gaertn)

C Palaric, S Atwi-Ghaddar, Q Gros, C Hano… - Journal of CO2 …, 2023 - Elsevier
Supercritical fluid extraction with carbon dioxide is nowadays one of the best approaches on
an economic and ecological point of view for the extraction of natural compounds from …

Green synthesis, characterization and electrochemical sensing of silymarin by ZnO nanoparticles: Experimental and DFT studies

D Sharma, MI Sabela, S Kanchi, K Bisetty… - Journal of …, 2018 - Elsevier
The use of plant extracts provides a biologically inspired route for the synthesis of
nanoparticles, which have received a significant interest worldwide. ZnO nanomaterials …

A DFT-based analysis of adsorption of Cd2+, Cr3+, Cu2+, Hg2+, Pb2+, and Zn2+, on vanillin monomer: a study of the removal of metal ions from effluents

IHS Ribeiro, DT Reis, DH Pereira - Journal of Molecular Modeling, 2019 - Springer
The density functional theory was used to understand the adsorption process of Cd (II), Cr
(III), Cu (II), Hg (II), Pb (II), and Zn (II) ions with the methacrylate monomer derived of vanillin …

Solubility and thermodynamic function of vanillin in ten different environmentally benign solvents

F Shakeel, N Haq, NA Siddiqui - Food chemistry, 2015 - Elsevier
The solubility of vanillin in ten different environmentally benign solvents namely water,
ethanol, ethylene glycol (EG), ethyl acetate (EA), isopropanol (IPA), propylene glycol (PG) …

Solubility of bioactive compound hesperidin in six pure solvents at (298.15 to 333.15) K

MK Anwer, R Al-Shdefat, S Jamil, P Alam… - Journal of Chemical & …, 2014 - ACS Publications
Temperature-dependent solubility data of bioactive compound hesperidin has not been
reported in any solvent in the literature so far. Therefore, the aim of the current study was to …

Solubility, molecular interactions and mixing thermodynamic properties of piperine in various pure solvents at different temperatures

S Alshehri, N Haq, F Shakeel - Journal of Molecular Liquids, 2018 - Elsevier
In this study, the solubility, molecular interactions and mixing thermodynamic properties of a
poorly water soluble bioactive compound piperine in twelve different pure solvents namely …

Solubility and thermodynamics of ferulic acid in different neat solvents: Measurement, correlation and molecular interactions

F Shakeel, MM Salem-Bekhit, N Haq… - Journal of Molecular …, 2017 - Elsevier
In the present investigation, the solubility of a bioactive compound ferulic acid (FA) in various
neat solvents namely “water, methanol, ethanol, isopropanol (IPA), ethylene glycol (EG) …

Flavonoids-based nanomedicine for the treatment of liver fibrosis: A recent progress

KS Harini, E Devaraj - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Liver fibrosis remains a life-threatening pathological condition, which might lead to
complications like cirrhosis and hepatocellular carcinoma when left untreated. The lack of …