[HTML][HTML] Cefiderocol either in monotherapy or combination versus best available therapy in the treatment of carbapenem-resistant Acinetobacter baumannii infections …

L Onorato, I de Luca, C Monari, N Coppola - Journal of Infection, 2024 - Elsevier
Background The best treatment for carbapenem-resistant Acinetobacter baumannii (CRAB)
infections is still a matter of debate. Objectives To describe the outcomes of patients treated …

Carbapenem-resistant Klebsiella pneumoniae: the role of plasmids in emergence, dissemination, and evolution of a major clinical challenge

V Di Pilato, S Pollini, V Miriagou… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction Klebsiella pneumoniae is a major agent of healthcare-associated infections and
a cause of some community-acquired infections, including severe bacteremic infections …

Performance evaluation of Bruker UMIC® microdilution panel and disc diffusion to determine cefiderocol susceptibility in Enterobacterales, Acinetobacter baumannii …

G Bianco, M Boattini, S Comini, P Gaibani… - European Journal of …, 2024 - Springer
Purpose Cefiderocol susceptibility testing (AST) represents an open challenge for clinical
microbiology. Herein, we evaluated the performance of the UMIC® Cefiderocol broth …

[HTML][HTML] Cefiderocol Is an Effective Topical Monotherapy for Experimental Extensively Drug-Resistant Pseudomonas aeruginosa Keratitis

EG Romanowski, SM Mumper, HQ Shanks… - Ophthalmology …, 2024 - Elsevier
Purpose To test cefiderocol, a siderophore-cephalosporin antibiotic for topical monotherapy
treatment of experimental extensively drug-resistant (XDR) Pseudomonas aeruginosa …

[HTML][HTML] Novel Antibiotics for Gram-Negative Nosocomial Pneumonia

MP Almyroudi, A Chang, I Andrianopoulos… - Antibiotics, 2024 - ncbi.nlm.nih.gov
Nosocomial pneumonia, including hospital-acquired pneumonia and ventilator-associated
pneumonia, is the leading cause of death related to hospital-acquired infections among …

Use of Cefiderocol in Adult Patients: Descriptive Analysis from a Prospective, Multicenter, Cohort Study

DR Giacobbe, L Labate, C Russo Artimagnella… - Infectious Diseases and …, 2024 - Springer
Introduction Cefiderocol is a siderophore cephalosporin showing activity against various
carbapenem-resistant Gram-negative bacteria (CR-GNB). No data currently exist about real …

Current developments and prospects of the antibiotic delivery systems

K Kharga, S Jha, T Vishwakarma… - Critical Reviews in …, 2024 - Taylor & Francis
Antibiotics have remained the cornerstone for the treatment of bacterial infections ever since
their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria …

Cefiderocol susceptibility of Achromobacter spp.: study of an accurately identified collection of 230 strains

V Jean-Pierre, P Sorlin, A Pantel, R Chiron… - Annals of Clinical …, 2024 - Springer
Background Achromobacter spp. are opportunistic pathogens, mostly infecting
immunocompromised patients and patients with cystic fibrosis (CF) and considered as …

Treatment Strategies of Colistin Resistance Acinetobacter baumannii Infections

A Papazachariou, RN Tziolos, S Karakonstantis… - Antibiotics, 2024 - mdpi.com
Acinetobacter baumannii has emerged as a pressing challenge in clinical practice, mainly
due to the development of resistance to multiple antibiotics, including colistin, one of the last …

Cefiderocol for resistant Gram negatives: linking in vitro activity with clinical effectiveness

F Patauner, E Durante-Mangoni - Clinical Microbiology and Infection, 2023 - Elsevier
In this Commentary, we discuss the main findings of a systematic review with meta-analysis
of in vitro susceptibility data for cefiderocol against gram-negative bacilli. We then put these …