[HTML][HTML] Systemic treatments for atopic dermatitis (eczema): systematic review and network meta-analysis of randomized trials

AWL Chu, MM Wong, DG Rayner, GH Guyatt… - Journal of Allergy and …, 2023 - Elsevier
Background Atopic dermatitis (AD) is an inflammatory skin condition with multiple systemic
treatments and uncertainty regarding their comparative impact on AD outcomes. Objective …

Commensal Cutibacterium acnes induce epidermal lipid synthesis important for skin barrier function

S Almoughrabie, L Cau, K Cavagnero, AM O'Neill… - Science …, 2023 - science.org
Lipid synthesis is necessary for formation of epithelial barriers and homeostasis with
external microbes. An analysis of the response of human keratinocytes to several different …

Pesticides and their impairing effects on epithelial barrier integrity, dysbiosis, disruption of the AhR signaling pathway and development of immune-mediated …

C Lima, MAP Falcão, JGS Rosa, GR Disner… - International Journal of …, 2022 - mdpi.com
The environmental and occupational risk we confront from agricultural chemicals increases
as their presence in natural habitats rises to hazardous levels, building a major part of the …

Bleach baths enhance skin barrier, reduce itch but do not normalize skin dysbiosis in atopic dermatitis

A Stolarczyk, N Perez-Nazario, SA Knowlden… - Archives of …, 2023 - Springer
Studies have demonstrated that bleach baths improve atopic dermatitis (AD) severity;
however, the effects on itch, skin barrier, and cutaneous microbial composition are less …

Update on atopic dermatitis

C Kellogg, J Smogorzewski - Advances in Pediatrics, 2023 - advancesinpediatrics.com
INTRODUCTION Atopic dermatitis (AD) is a chronic inflammatory skin disorder with a
lifetime prevalence of up to 20% which can occur at any age but is most common among …

Epicutaneous sensitization and food allergy: preventive strategies targeting skin barrier repair—facts and challenges

A Dębińska, B Sozańska - Nutrients, 2023 - mdpi.com
Food allergy represents a growing public health and socio-economic problem with an
increasing prevalence over the last two decades. Despite its substantial impact on the …

Aquaporins are one of the critical factors in the disruption of the skin barrier in inflammatory skin diseases

PM Tricarico, D Mentino, A De Marco… - International Journal of …, 2022 - mdpi.com
The skin is the largest organ of the human body, serving as an effective mechanical barrier
between the internal milieu and the external environment. The skin is widely considered the …

Phenotypic and endotypic determinants of atopic dermatitis severity from the Atopic Dermatitis Research Network (ADRN) Registry

EL Simpson, A De Benedetto, M Boguniewicz… - The Journal of Allergy …, 2023 - Elsevier
Background Atopic dermatitis (AD) is a chronic inflammatory skin condition with a highly
variable clinical phenotype. Objective This study aimed to identify historical and clinical …

Atopic March or Atopic Multimorbidity—Overview of Current Research

I Mrkić Kobal, D Plavec, Ž Vlašić Lončarić, I Jerković… - Medicina, 2023 - mdpi.com
The atopic march encompasses a sequence of allergic conditions, including atopic
dermatitis, food allergy, allergic rhinitis, and asthma, that frequently develop in a sequential …

Correlation of body mass index with epidermal biophysical properties varies with gender in Chinese

L Ye, Q Lai, S Wen, X Wang, B Yang… - Skin Pharmacology and …, 2022 - karger.com
Background: Epidermal function is associated with diabetes and renal disease. Whether
obesity can reflect the changes in epidermal function is not clear yet. Objective: We …