1, 3, 4-Thiadiazoles: A potent multi targeted pharmacological scaffold

S Haider, MS Alam, H Hamid - European journal of medicinal chemistry, 2015 - Elsevier
Despite a significant work on thiadiazoles, continuous efforts are still being made to identify
novel heterocyclic compounds with potent biological activities. This review may help the …

Synthesis of novel pyrazole derivatives and evaluation of their antidepressant and anticonvulsant activities

M Abdel-Aziz, GEDA Abuo-Rahma… - European journal of …, 2009 - Elsevier
Substituted carboxylic acid hydrazides 1a–d reacted with ethenetetracarbonitril 2 in dimethyl
formamide with the formation of diacylhydrazines 4a–d and 5-amino-1-substiuted pyrazole …

Synthesis and biological properties of dihydro-oxadiazine-based heterocyclic derivatives

S Ke, X Cao, Y Liang, K Wang… - Mini Reviews in …, 2011 - ingentaconnect.com
Dihydro-oxadiazine and its derivatives have been demonstrated to be important heterocyclic
scaffold platform with bioactive diversity, which present wide activities such as …

[HTML][HTML] Optimized POCl3-assisted synthesis of 2-amino-1, 3, 4-thiadiazole/1, 3, 4-oxadiazole derivatives as anti-influenza agents

J Dong, Q Pei, P Wang, Q Ma, W Hu - Arabian Journal of Chemistry, 2022 - Elsevier
Although recent decades have witnessed the synthesis of 1, 3, 4-thiadiazoles via
phosphorus POCl 3-promoted cyclization reaction, simultaneous access to 2-amino-1, 3, 4 …

[PDF][PDF] Synthesis of 1, 3, 4-thiadiazole derivatives and microbiological activities: A review

GAD Barbosa, AP de Aguiar - Rev. Virtual Quim, 2019 - s3.sa-east-1.amazonaws.com
Bacterial resistance associated to different antibiotics is a limitation for the treatment of
infections and this has stimulated the development of new antimicrobial agents. In this …

Efficient one-pot synthesis of substituted 2-amino-1, 3, 4-oxadiazoles

ELP Chekler, HM Elokdah, J Butera - Tetrahedron Letters, 2008 - Elsevier
A convenient one-pot method for the preparation of substituted 2-amino-1, 3, 4-oxadiazoles
has been developed. The method is a significant improvement over previously reported …

1-Cyanoacetylthiosemicarbazides: Recent advances in their synthesis, reactivity in heterocyclization, and bio-applications

S Bondock, N Alabbad, A Hossan… - Mini-Reviews in …, 2024 - ingentaconnect.com
The synthesis of 1-cyanoacetylthiosemicarbazides is at the apex attention of researchers
due to their multifaced reactivity as versatile precursors in the synthesis of mono-, bi-, and …

[PDF][PDF] Hydrazinecarbothioamide group in the synthesis of heterocycles

AA Aly, AB Brown, TI El-Emary, AMM Ewas… - Arkivoc, 2009 - repository.fit.edu
Hydrazinecarbothioamide group in the synthesis of heterocycles Page 1 Florida Institute of
Technology Scholarship Repository @ Florida Tech Chemistry and Chemical Engineering Faculty …

Heterocyclic synthesis with 4-benzoyl-1-cyanoacetylthiosemicarbazide: selective synthesis of some thiazole, triazole, thiadiazine, pyrrylthiazole, and pyrazolo [1, 5-a] …

S Bondock, AEG Tarhoni, AA Fadda - Monatshefte Für Chemie-Chemical …, 2008 - Springer
4-Benzoyl-1-cyanoacetylthiosemicarbazide undergoes coupling reaction with aromatic
diazonium chloride to afford (arylhydrazono) thiosemicarbazide, which was reacted with …

[PDF][PDF] Recent progress in the synthesis and applications of heterocycles derived from enaminonitriles

S Bondock, A El-Gaber Tarhoni… - Current Organic …, 2011 - academia.edu
Recent progress in the synthesis and use of enaminonitriles as precursors for carbocyclic
and heterocyclic compounds is reviewed. The synthetic routes for preparation of …