Application of continuous epidural anesthesia in transforaminal lumbar endoscopic surgery: a prospective randomized controlled trial

T Xu, R Tian, P Qiao, Z Han… - Journal of International …, 2019 - journals.sagepub.com
Objective This study aimed to compare intraoperative lower back pain and leg pain, surgical
time, and intraoperative X-ray dose in patients offered local infiltration anesthesia or …

Protocol for biospecimen collection and analysis within the BACPAC research program

AJ Fields, S Dudli, A Schrepf, A Kim, B Pham… - Pain …, 2023 - academic.oup.com
Abstract The Biospecimen Collection and Processing Working Group of the National
Institutes of Health (NIH) HEAL Initiative BACPAC Research Program was charged with …

Urine metabolomics profiling of lumbar disc herniation and its traditional Chinese medicine subtypes in patients through gas chromatography coupled with mass …

L Shan, J Yang, S Meng, H Ruan, L Zhou… - Frontiers in Molecular …, 2021 - frontiersin.org
Lumbar disc herniation (LDH) possesses complex pathogenesis, which has not been well
elucidated yet. To date, specific or early diagnosis of LDH remains unavailable, resulting in …

Pharmacogenetic profiling and individualised therapy in the treatment of degenerative spinal conditions

JM McDonnell, B Rigney, J Storme, DP Ahern… - Irish Journal of Medical …, 2023 - Springer
Patients presenting with degenerative spinal changes are often poor surgical candidates
due to associated co-morbidities, frailty, or sarcopenia. Additionally, surgeries of a …

Transcriptome analysis identifies genes involved with the development of umbilical hernias in pigs

MR Souza, AMG Ibelli, IR Savoldi, ME Cantão… - PLoS …, 2020 - journals.plos.org
Umbilical hernia (UH) is one of the most frequent defects affecting pig production, however,
it also affects humans and other mammals. UH is characterized as an abnormal protrusion of …

Association of GSDMC polymorphisms with lumbar disc herniation among Chinese Han population

J Wu, Y Sun, Z Xiong, J Liu, H Li, Y Liu… - International Journal …, 2020 - Wiley Online Library
Lumbar disc herniation (LDH) is a relatively common spinal disease, but its pathogenesis is
still unknown. Numerous studies have shown that LDH is closely correlated with …

Efficacy and safety of bushen huoxue formula in patients with discogenic low-back pain: a double-blind, randomized, placebo-controlled trial

J Zhan, K Li, L Zhu, S Wang, M Feng, X Wei… - Chinese Journal of …, 2022 - Springer
Objective To assess the efficacy and safety of Bushen Huoxue Formula (BSHXF) for the
treatment of discogenic low-back pain (DLBP). Methods This was a parallel, double-blind …

软骨细胞外基质基因调控与遗传缺陷研究新进展

金渝瑜, 罗飞宏 - 临床儿科杂志, 2024 - jcp.xinhuamed.com.cn
生长板软骨的生长发育是一个精密的生物学过程, 受到细胞外基质, 细胞内信号, 旁分泌信号,
内分泌信号等综合调控. 细胞外基质在软骨细胞的结构支持中起着关键作用 …

Computational functional genomics-based AmpliSeq™ panel for next-generation sequencing of key genes of pain

D Kringel, S Malkusch, E Kalso, J Lötsch - International journal of …, 2021 - mdpi.com
The genetic background of pain is becoming increasingly well understood, which opens up
possibilities for predicting the individual risk of persistent pain and the use of tailored …

[HTML][HTML] Decoding the Genetic Threads of Disc Degeneration

A Biswas, B Garg - Indian Spine Journal, 2024 - journals.lww.com
Degenerative disc disease (DDD) is a prevalent musculoskeletal disorder characterized by
the progressive degeneration of intervertebral discs, often leading to chronic low back pain …