Non-coding RNAs and prediction of preeclampsia in the first trimester of pregnancy

M Ogoyama, H Takahashi, H Suzuki, A Ohkuchi… - Cells, 2022 - mdpi.com
Preeclampsia (PE) is a major cause of maternal and perinatal morbidity and mortality. The
only fundamental treatment for PE is the termination of pregnancy. Therefore, not only …

The pathophysiological, genetic, and hormonal changes in preeclampsia: A systematic review of the molecular mechanisms

YT Chiang, KM Seow, KH Chen - International Journal of Molecular …, 2024 - mdpi.com
Preeclampsia, a serious complication of pregnancy, involves intricate molecular and cellular
mechanisms. Fetal microchimerism, where fetal cells persist within maternal tissues and in …

Circulating extracellular vesicular microRNA signatures in early gestation show an association with subsequent clinical features of pre-eclampsia

S Ghosh, S Thamotharan, J Fong, MYY Lei… - Scientific Reports, 2024 - nature.com
In a prospective cohort of subjects who subsequently developed preeclampsia (PE, n= 14)
versus remaining healthy (NORM, n= 12), early gestation circulating extracellular vesicles …

Exosomal small RNA profiling in first-trimester maternal blood explores early molecular pathways of preterm preeclampsia

L Gál, Á Fóthi, G Orosz, S Nagy, NG Than… - Frontiers in …, 2024 - frontiersin.org
Introduction Preeclampsia (PE) is a severe obstetrical syndrome characterized by new-onset
hypertension and proteinuria and it is often associated with fetal intrauterine growth …

Non-coding RNAs in airway diseases: a brief overview of recent data

GD Albano, R Gagliardo, AM Montalbano, M Profita - Cancers, 2022 - mdpi.com
Simple Summary Nc-RNA are microRNA, long-coding RNA, and circulating-RNA. In this
review we report most recent data regarding the role of nc-RNA in airway diseases, with a …

The role of cluster C19MC in pre-eclampsia development

I Jaszczuk, I Winkler, D Koczkodaj… - International Journal of …, 2022 - mdpi.com
Pre-eclampsia is a placenta-related complication occurring in 2–10% of all pregnancies.
miRNAs are a group of non-coding RNAs regulating gene expression. There is evidence …

The prospect of genomic, transcriptomic, epigenetic and metabolomic biomarkers for the personalized prevention of type 2 diabetes and cardiovascular diseases

A Zeljkovic, M Mihajlovic, S Vujcic… - Current Vascular …, 2023 - ingentaconnect.com
Cardiometabolic diseases, such as type 2 diabetes mellitus (DM) and cardiovascular
disease (CVD), are a great health concern. The strategies aimed to increase awareness and …

The long noncoding RNA TARID regulates the CXCL3/ERK/MAPK pathway in trophoblasts and is associated with preeclampsia

L Liao, M Liu, Y Gao, X Wei, Y Yin, L Gao… - Reproductive Biology and …, 2022 - Springer
Background The widely accepted explanation of preeclampsia (PE) pathogenesis is
insufficient trophoblast invasion and impaired uterine spiral artery remodeling. However, the …

IGF2BP2 enhances LincRNA01116 stability via m6A: A potential biomarker and therapeutic target for patients with pre‐eclampsia

T Zhang, X Tang, Y Zhu, C Wang… - Journal of Cellular …, 2023 - Wiley Online Library
Pre‐eclampsia (PE) is a serious complication in pregnant women characterized by failure of
placental remodeling and is one of the primary causes of changes in the placental structure …

circPTK2 promotes proliferation, migration and invasion of trophoblast cells through the miR-619/WNT7B pathway in preeclampsia

S Wu, L Liu, T Tao, J Xiao, H Yang, X Yu… - Molecular and Cellular …, 2023 - Springer
It has been shown that the circular RNA (circRNA) circPTK2 modulates many types of
diseases. However, the possible functions as well as the molecular mechanisms of circPTK2 …