The reversible phosphorylation of proteins ranks among the most important posttranslational
modifications that occur in the cell. In the last several decades, protein phosphorylation has …

This review traces the history and logical progression of methods for quantitative analysis of
enzyme kinetics from the 1913 Michaelis and Menten paper to the application of modern …

Nearly 100 years ago Michaelis and Menten published their now classic paper [Michaelis,
L., and Menten, ML (1913) Die Kinetik der Invertinwirkung. Biochem. Z. 49, 333–369] in …

The Arp2/3 complex is a stable assembly of seven protein subunits including two actin-
related proteins (Arp2 and Arp3) and five novel proteins. Previous work showed that this …

A major pathway in the reaction between Fe (II) and H2O2 at pH 6–7 in non-coordinating
buffers exhibits inverse kinetic dependence on [H+] and leads to oxidation of dimethyl …

We describe a new dynamic kinetic simulation program that allows multiple data sets to be fit
simultaneously to a single model based on numerical integration of the rate equations …

MOTIVATION: Genome sequencing projects and further systematic functional analyses of
complete gene sets are producing an unprecedented mass of molecular information for a …

The kinetic and thermodynamic characteristics of polymerizations following a cooperative,
nucleation–elongation mechanism are discussed in comparison to those of non …

E'-Dn+ r* ED n+ r**-s [Pl ED n+ 1 where E, D, N, and P represent T7 DNA polymerase, DNA
primer/template, deoxynucleoside triphosphate, and inorganic pyrophosphate, respectively …

Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania
16802 Received September 19, 1986; Revised Manuscript Received January 29, 1987 …