Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke

C Zerna, G Thomalla, BCV Campbell, JH Rha, MD Hill - The Lancet, 2018 - thelancet.com
Even though stroke presents as a variety of clinical syndromes, neuroimaging is the most
important biomarker to help differentiate between stroke subtypes and assess treatment …

Diagnosis and management of acute ischaemic stroke

R Hurford, A Sekhar, TAT Hughes, KW Muir - Practical Neurology, 2020 - pn.bmj.com
Acute ischaemic stroke is a major public health priority and will become increasingly
relevant to neurologists of the future. The cornerstone of effective stroke care continues to be …

MRI-guided thrombolysis for stroke with unknown time of onset

G Thomalla, CZ Simonsen, F Boutitie… - … England Journal of …, 2018 - Mass Medical Soc
Background Under current guidelines, intravenous thrombolysis is used to treat acute stroke
only if it can be ascertained that the time since the onset of symptoms was less than 4.5 …

Utstein recommendation for emergency stroke care

AG Rudd, C Bladin, P Carli… - … journal of stroke, 2020 - journals.sagepub.com
Background Recent advances in treatment for stroke give new possibilities for optimizing
outcomes. To deliver these prehospital care needs to become more efficient. Aim To …

Traumatic brain injury is associated with both hemorrhagic stroke and ischemic stroke: a systematic review and meta-analysis

D Qu, W Li, S Zhang, R Li, H Wang… - Frontiers in Neuroscience, 2022 - frontiersin.org
Background Traumatic brain injury (TBI) is considered a risk factor for the development of
stroke (Hemorrhagic Stroke and Ischemic Stroke). We performed this systemic review and …

Wake-up stroke: from pathophysiology to management

L Peter-Derex, L Derex - Sleep medicine reviews, 2019 - Elsevier
Wake-up strokes (WUS) are strokes with unknown exact time of onset as they are noted on
awakening by the patients. They represent 20% of all ischemic strokes. The …

Development and external validation of a stability machine learning model to identify wake-up stroke onset time from MRI

L Jiang, S Wang, Z Ai, T Shen, H Zhang, S Duan… - European …, 2022 - Springer
Objectives To develop and externally validate a machine learning (ML) model based on
diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) to identify …

Sleep apnea and stroke

M McDermott, DL Brown - Current opinion in neurology, 2020 - journals.lww.com
Sleep apnea is a well established independent risk factor for stroke that confers an
approximately two-fold increased risk of incident stroke. Sleep apnea is highly prevalent …

Synthetic T2 mapping is correlated with time from stroke onset: a future tool in wake-up stroke management?

T Duchaussoy, JF Budzik, L Norberciak, L Colas… - European …, 2019 - Springer
Objectives FLAIR-DWI mismatch is an effective method to select eligible wake-up stroke
(WUS) patients for intravenous thrombolysis, but shows limitations in the case of subtle …

Intravenous thrombolysis for acute ischemic stroke: a bridge between two centuries

G Tsivgoulis, O Kargiotis… - Expert Review Of …, 2017 - Taylor & Francis
Introduction: Intravenous tissue-plasminogen activator (tPA) remains the only approved
systemic reperfusion therapy suitable for most patients presenting timely with acute ischemic …