BACKGROUND Recurrent miscarriage and pre-eclampsia are common reproductive
disorders, but their causes are often unknown. Recent evidence has provided new insight …

The hallmark of human early pregnancy is the accumulation of a unique population of
Natural Killer (dNK) cells at the main maternal-fetal interface, the decidua basalis. dNK cells …

Deficiency in decidualization has been widely regarded as an important cause of
spontaneous abortion. Generalized decidualization also includes massive infiltration and …

Purpose: Tumor infiltrating T lymphocytes in colorectal cancer (CRC) have prognostic
impact, but the role of natural killer (NK) cells in CRC tissue is unclear. The contribution of …

The tumor microenvironment can polarize innate immune cells to a proangiogenic
phenotype. Decidual natural killer (dNK) cells show an angiogenic phenotype, yet the role …

Review of mechanisms of uterine leukocyte infiltration and the potential roles of each
subpopulation of leukocytes in relation to pregnancy and parturition. No other organ in the …

Research on the placenta as the interface between the mother and the fetus has been
undertaken for some 150 years, and in 2 subsequent reviews, we attempted to summarize …

Tumor-infiltrating leukocytes are often induced by the cancer microenvironment to display a
protumor, proangiogenic phenotype. This “polarization” has been described for several …

A large body of data shows that Natural Killer (NK) cells are immune effectors exerting a
potent cytolytic activity against tumors and virus infected cells. The discovery and …

Overt and subclinical maternal infections in pregnancy can have multiple and significant
pathological consequences for the developing fetus, leading to acute perinatal …