Air separation units are one of the prime examples for studies on demand side management
and (non‐) linear model predictive control due to their high power consumption and energy …

This paper presents surrogate models of dissolution behavior to identify the critical input
parameters in tablet manufacturing processes. Dissolution behavior is a critical quality …

Steel production requires enough oxygen, which is produced by cryogenic air separation
(ASU) with a large load, high power, and slow adjustment. Facing complex oxygen …

Accurate physical dynamic models applied as digital twins are vital for developing advanced
control strategies and optimizing dynamic plant operation. First principle models are often …

The conceptual process design of novel bioprocesses in biorefinery setups is an important
task, which remains yet challenging due to several limitations. We propose a novel …

The optimal operation of multi-energy systems requires optimization models that are
accurate and computationally efficient. In practice, models are mostly generated manually …

In this work, a novel iterative least squares method is proposed to approximate nonlinear
functions with continuous piecewise linear (CPWL) functions, where the continuity is …

To realize adaptive operation planning with MILP unit commitment, piecewise-linear
approximations of the functions that describe the operating behavior of devices in the energy …

The optimization of process systems within the field of Chemical Engineering often confronts
uncertainties that can exert significant influences on the performance and dependability of …

The presented work focuses on the value chain optimization of a conceptually designed
biorefinery, considering the plant capacity and other logistic and design constraints. An …