Mitosis mediates the accurate separation of daughter cells, and abnormalities are closely
related to cancer progression. KIF11, a member of the kinesin family, plays a vital role in the …

Kinesins are widely expressed, microtubule‐dependent motors that play vital roles in
microtubule‐associated cellular activities, such as cell division and intracellular transport …

The photoreceptor cilium is vital for maintaining the structure and function of the retina.
However, the molecular mechanisms underlying the photoreceptor cilium integrity and …

Retinoic acid (RA), an active derivative of vitamin A, is critical for the neural system
development. During the neural development, the RA/RA receptor (RAR) pathway …

Cuproptosis is a recently reported novel form of cell death, which is involved in the
regulation of tumor progression. However, the specific role of cuproprosis in hepatocellular …

The heat shock protein 70 (HSP70) is a conserved molecular chaperone and proteostasis
regulator that protects cells from pharmacological stress and promotes drug resistance in …

The ubiquitin proteasome system regulates key cellular processes in normal and in cancer
cells. Herein, we review published data on the role of ubiquitin ligases in the four major …

The CRL1 complex, also known as the SCF complex, is a ubiquitin ligase that in mammals
consists of an adaptor protein (SKP1), a scaffold protein (CUL1), a RING finger protein …

旨在预测奶牛microRNA-223 (bta-miR-223) 的候选靶基因, 并对其进行蛋白质互作分析,
信号通路富集分析, 构建其可能参与的调控网络, 为bta-miR-223 参与乳腺炎抗性调控机制研究 …

Ovarian cancer is the most lethal gynecologic cancer (1). We sought to identify genes
associated with high-grade serous ovarian cancer (HGSC) by comparing global gene …