Transforming growth factor-beta (TGF-β) signaling in cancer-A betrayal within

AB Baba, B Rah, GR Bhat, I Mushtaq… - Frontiers in …, 2022 - frontiersin.org
A ubiquitously expressed cytokine, transforming growth factor-beta (TGF-β) plays a
significant role in various ongoing cellular mechanisms. The gain or loss-of-function of TGF …

STAT3 as a potential therapeutic target in triple negative breast cancer: a systematic review

JJ Qin, L Yan, J Zhang, WD Zhang - Journal of Experimental & Clinical …, 2019 - Springer
Triple negative breast cancer (TNBC), which is typically lack of expression of estrogen
receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 …

Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and …

R Ahmad, M Riaz, A Khan, A Aljamea… - Phytotherapy …, 2021 - Wiley Online Library
Reishi owes an exceptional value in nutritional, cosmeceutical, and medical treatments;
however, none of the studies has provided its future‐driven critical assessment. This study …

Inflammation-induced tumorigenesis and metastasis

S Hibino, T Kawazoe, H Kasahara, S Itoh… - International journal of …, 2021 - mdpi.com
Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …

The signaling pathways and targets of traditional Chinese medicine and natural medicine in triple-negative breast cancer

Z Yang, Q Zhang, L Yu, J Zhu, Y Cao, X Gao - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Triple-negative breast cancer (TNBC) has a poorer
prognosis than other subtypes due to its strong invasion and higher risk of distant …

Targeted degradation of transcription factors by TRAFTACs: transcription factor targeting chimeras

KTG Samarasinghe, S Jaime-Figueroa, M Burgess… - Cell chemical …, 2021 - cell.com
Many diseases, including cancer, stem from aberrant activation or overexpression of
oncoproteins that are associated with multiple signaling pathways. Although proteins with …

An insight into the cancer stem cell survival pathways involved in chemoresistance in triple-negative breast cancer

H Qayoom, NA Wani, B Alshehri, MA Mir - Future oncology, 2021 - Taylor & Francis
Triple-negative breast cancer (TNBC) is the most complex, aggressive and fatal subtype of
breast cancer. Owing to the lack of targeted therapy and heterogenic nature of TNBC …

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical …

JH Wong, TB Ng, HHL Chan, Q Liu, GCW Man… - Applied Microbiology …, 2020 - Springer
This article reviews mushrooms with anti-breast cancer activity. The mushrooms covered
which are better known include the following: button mushroom Agaricus bisporus, Brazilian …

[HTML][HTML] The role and specific mechanism of OCT4 in cancer stem cells: a review

Q Zhang, Z Han, Y Zhu, J Chen… - International journal of …, 2020 - synapse.koreamed.org
Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …

Anti-cancer potential of edible/medicinal mushrooms in breast cancer

MB Gariboldi, E Marras, N Ferrario, V Vivona… - International Journal of …, 2023 - mdpi.com
Edible/medicinal mushrooms have been traditionally used in Asian countries either in the
cuisine or as dietary supplements and nutraceuticals. In recent decades, they have aroused …