Simple Summary The incidence of renal cell carcinoma (RCC) rises globally with the highest
rates in developed countries. This indicates not only the impact of advanced imaging, but …

Farnesyl-diphosphate farnesyltransferase 1 (FDFT1, squalene synthase), a membrane-
associated enzyme, synthesizes squalene via condensation of two molecules of farnesyl …

We have profiled, for the first time, an evolving human metastatic microenvironment by
measuring gene expression, matrisome proteomics, cytokine and chemokine levels …

Abstract Fibronectin 1 (FN1) is involved in cell adhesion and migration processes including
embryogenesis, wound healing, blood coagulation, host defense, metastasis, and …

Objective Patients with increased PD-L1+ host cells in tumours are more potent to benefit
from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the …

Background & Aims Increasing grade of pancreatic intraepithelial neoplasia (PanIN) has
been associated with progression to pancreatic ductal adenocarcinoma (PDAC). However …

Collagen VI is significant in the progression of numerous types of cancer. Type VI collagen
consists of three α‑chains and collagen VI α3 (COL6A3) encodes the α3 chain. The …

Aims Fibronectin (FN) has attracted interest in cancer research, owing to its role in tumour
progression. The aims of this study were to investigate the expression and clinical relevance …

Objective: To investigate the correlation of fibronectin 1 (FN1) expression with prognosis and
tumor-infiltrating immune cells in breast cancer (BRCA). Methods: FN1 mRNA and protein …

Background and aims The complex process of cancer metastasis remains the least
understood. Tumor cells alter their protein expression profile to survive from the tumor …