Chronic kidney disease (CKD), defined as the presence of irreversible structural or
functional kidney damages, increases the risk of poor outcomes due to its association with …

Acute kidney injury (AKI) is a major public health concern associated with high morbidity and
mortality. Despite decades of research, the pathogenesis of AKI remains incompletely …

In contrast to normal type I collagen (Col1) heterotrimer (α1/α2/α1) produced by fibroblasts,
pancreatic cancer cells specifically produce unique Col1 homotrimer (α1/α1/α1). Col1 …

Ischemia reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The role of
N6-methyladenosine (m6A) modification in AKI remains unclear. Here, we characterize the …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are worldwide public health
problems affecting millions of people and have rapidly increased in prevalence in recent …

Reactive oxygen species (ROS) scavenging therapy toward acute kidney injury (AKI) is
promising, but no effective ROS scavenging drug has been developed yet. Moreover, cell …

Acute kidney injury (AKI) is associated with high mortality and morbidity with no effective
treatment available at present, which greatly escalates the risk of chronic kidney disease …

Abstract Ischemic/reperfusion (I/R) injury causes a series of serious clinical problems
associated with high morbidity and mortality in various disorders, such as acute kidney injury …

Epigenetics refers to heritable changes in gene expression patterns not caused by an
altered nucleotide sequence, and includes non-coding RNAs and covalent modifications of …

Aims Genetic and pharmacological inhibition of mitochondrial fission induced by acute
myocardial ischaemia/reperfusion injury (IRI) has been shown to reduce myocardial infarct …